E-ISSN 0976-2779 | ISSN 0975-8453
 

Review Article 


Potentiometric Determination of Chlordiazepoxide Using PVC and Carbon Paste Electrodes

Omar S. Hassan, Huda Ghalib Salman, Omar Adnan Hashem, Amina M. Abass.

Abstract
potentiometric technique is described for determination of chlordiazepoxide .A sensitive rapid ,simple method for evaluation of Chlordiazepoxide in pharmaceutical preparations and pure by using modified PVC and carbon paste electrodes is established. Chlordiazepoxide selective electrodes were produced as of chlordiazepoxide- phosphotungetic acid as an electroactive with n-Di-butyl phthalate(DBPH) in THF as a solvent. Various factors influencing the response of electrodes were improved and plotted the calibration curve . PVC and Carbon paste electrode constructed were gave a Nernstian response about 54.00, 57.51 mVdecade−1, respectively with an extensive range of concentration , from 3.0×10-6-1.0×10-2 and 1.8×10-6-1.0×10-2 M, for PVC, carbon paste electrode, respectively, with a little detection limit near to 2.2×10-5, 1.4×10-5M. The pH values for quantifiable was detected .Lastly, the projected electrode was used as effectively for the determination of chlordiazepoxide by potentiometric techniques in pure and pharmaceutical samples.

Key words: carbon paste electrodes, chlordiazepoxide, potentiometric method, ion selective electrode.


 
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How to Cite this Article
Pubmed Style

Omar S. Hassan, Huda Ghalib Salman, Omar Adnan Hashem, Amina M. Abass. Potentiometric Determination of Chlordiazepoxide Using PVC and Carbon Paste Electrodes. SRP. 2020; 11(6): 369-375. doi:10.31838/srp.2020.6.58


Web Style

Omar S. Hassan, Huda Ghalib Salman, Omar Adnan Hashem, Amina M. Abass. Potentiometric Determination of Chlordiazepoxide Using PVC and Carbon Paste Electrodes. http://www.sysrevpharm.org//?mno=116263 [Access: June 18, 2020]. doi:10.31838/srp.2020.6.58


AMA (American Medical Association) Style

Omar S. Hassan, Huda Ghalib Salman, Omar Adnan Hashem, Amina M. Abass. Potentiometric Determination of Chlordiazepoxide Using PVC and Carbon Paste Electrodes. SRP. 2020; 11(6): 369-375. doi:10.31838/srp.2020.6.58



Vancouver/ICMJE Style

Omar S. Hassan, Huda Ghalib Salman, Omar Adnan Hashem, Amina M. Abass. Potentiometric Determination of Chlordiazepoxide Using PVC and Carbon Paste Electrodes. SRP. (2020), [cited June 18, 2020]; 11(6): 369-375. doi:10.31838/srp.2020.6.58



Harvard Style

Omar S. Hassan, Huda Ghalib Salman, Omar Adnan Hashem, Amina M. Abass (2020) Potentiometric Determination of Chlordiazepoxide Using PVC and Carbon Paste Electrodes. SRP, 11 (6), 369-375. doi:10.31838/srp.2020.6.58



Turabian Style

Omar S. Hassan, Huda Ghalib Salman, Omar Adnan Hashem, Amina M. Abass. 2020. Potentiometric Determination of Chlordiazepoxide Using PVC and Carbon Paste Electrodes. Systematic Reviews in Pharmacy, 11 (6), 369-375. doi:10.31838/srp.2020.6.58



Chicago Style

Omar S. Hassan, Huda Ghalib Salman, Omar Adnan Hashem, Amina M. Abass. "Potentiometric Determination of Chlordiazepoxide Using PVC and Carbon Paste Electrodes." Systematic Reviews in Pharmacy 11 (2020), 369-375. doi:10.31838/srp.2020.6.58



MLA (The Modern Language Association) Style

Omar S. Hassan, Huda Ghalib Salman, Omar Adnan Hashem, Amina M. Abass. "Potentiometric Determination of Chlordiazepoxide Using PVC and Carbon Paste Electrodes." Systematic Reviews in Pharmacy 11.6 (2020), 369-375. Print. doi:10.31838/srp.2020.6.58



APA (American Psychological Association) Style

Omar S. Hassan, Huda Ghalib Salman, Omar Adnan Hashem, Amina M. Abass (2020) Potentiometric Determination of Chlordiazepoxide Using PVC and Carbon Paste Electrodes. Systematic Reviews in Pharmacy, 11 (6), 369-375. doi:10.31838/srp.2020.6.58





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