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Antibacterial and Anti-inflammatory Activities of Ethanol Extract Obtained from The Hooks of Uncaria tomentosa (Wild. Ex Schult) DC Originated Kalimantan, Indonesia

Warsidah, Dzul Fadly, Bohari.

Abstract
Uncaria tomentosa is one natural medicinal plant. The plant parts commonly harvested and utilized are the leaves and twigs. This study aimed to find out the benefit of the hook of U. tomentosa regarding the antibacterial and anti-inflammatory produces by phytochemical content. It was a Laboratory-based study. The primary material was the hooks of U. tomentosa (Wild. Ex Schult) DC collected from Kapuas Hulu, West Kalimantan, Indonesia, and extracted by Ethanol and Methanol maceration. The antibacterial was determined against Staphylococcus aureus and Salmonella Thypi; measured the transparent zone after 24 H incubation at 37 ºC. The anti-inflammatory activity was identified on the stability of red blood cells (RBCs) membrane by determining the percentage of hemolysis inhibition. The observation showed that ethanol extract had better phytochemical substances compared to methanol extract, and became a selected sample intended for antibacterial and anti-inflammatory identification. The higher concentration of ethanol extract led to an increased in bacterial growth inhibition. The ethanol extract showed a better impact against RBCs stability at level ≥ 50 ppm compared to 100 ppm aspirin with the EC50 was 5.21 ppm. The result indicates that ethanol extract derived from the hooks of Uncaria tomentosa (Wild. Ex Schult) DC origin Kalimantan, Indonesia provides the antibacterial and anti-inflammatory at once.

Key words: Uncaria tomentosa, antibacterial, phytochemicals, anti-inflammatory, red blood cells


 
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How to Cite this Article
Pubmed Style

, Fadly D, Bohari . Antibacterial and Anti-inflammatory Activities of Ethanol Extract Obtained from The Hooks of Uncaria tomentosa (Wild. Ex Schult) DC Originated Kalimantan, Indonesia. SRP. 2020; 11(7): 65-70. doi:10.31838/srp.2020.7.11


Web Style

, Fadly D, Bohari . Antibacterial and Anti-inflammatory Activities of Ethanol Extract Obtained from The Hooks of Uncaria tomentosa (Wild. Ex Schult) DC Originated Kalimantan, Indonesia. http://www.sysrevpharm.org//?mno=117512 [Access: August 01, 2020]. doi:10.31838/srp.2020.7.11


AMA (American Medical Association) Style

, Fadly D, Bohari . Antibacterial and Anti-inflammatory Activities of Ethanol Extract Obtained from The Hooks of Uncaria tomentosa (Wild. Ex Schult) DC Originated Kalimantan, Indonesia. SRP. 2020; 11(7): 65-70. doi:10.31838/srp.2020.7.11



Vancouver/ICMJE Style

, Fadly D, Bohari . Antibacterial and Anti-inflammatory Activities of Ethanol Extract Obtained from The Hooks of Uncaria tomentosa (Wild. Ex Schult) DC Originated Kalimantan, Indonesia. SRP. (2020), [cited August 01, 2020]; 11(7): 65-70. doi:10.31838/srp.2020.7.11



Harvard Style

, Fadly, . D. & Bohari, . (2020) Antibacterial and Anti-inflammatory Activities of Ethanol Extract Obtained from The Hooks of Uncaria tomentosa (Wild. Ex Schult) DC Originated Kalimantan, Indonesia. SRP, 11 (7), 65-70. doi:10.31838/srp.2020.7.11



Turabian Style

, Dzul Fadly, and Bohari. 2020. Antibacterial and Anti-inflammatory Activities of Ethanol Extract Obtained from The Hooks of Uncaria tomentosa (Wild. Ex Schult) DC Originated Kalimantan, Indonesia. Systematic Reviews in Pharmacy, 11 (7), 65-70. doi:10.31838/srp.2020.7.11



Chicago Style

, Dzul Fadly, and Bohari. "Antibacterial and Anti-inflammatory Activities of Ethanol Extract Obtained from The Hooks of Uncaria tomentosa (Wild. Ex Schult) DC Originated Kalimantan, Indonesia." Systematic Reviews in Pharmacy 11 (2020), 65-70. doi:10.31838/srp.2020.7.11



MLA (The Modern Language Association) Style

, Dzul Fadly, and Bohari. "Antibacterial and Anti-inflammatory Activities of Ethanol Extract Obtained from The Hooks of Uncaria tomentosa (Wild. Ex Schult) DC Originated Kalimantan, Indonesia." Systematic Reviews in Pharmacy 11.7 (2020), 65-70. Print. doi:10.31838/srp.2020.7.11



APA (American Psychological Association) Style

, Fadly, . D. & Bohari, . (2020) Antibacterial and Anti-inflammatory Activities of Ethanol Extract Obtained from The Hooks of Uncaria tomentosa (Wild. Ex Schult) DC Originated Kalimantan, Indonesia. Systematic Reviews in Pharmacy, 11 (7), 65-70. doi:10.31838/srp.2020.7.11





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