E-ISSN 0976-2779 | ISSN 0975-8453
 

Review Article 


Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis

Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti.

Abstract
The aim of this study was to find the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of sappan wood ethanol extract (Caesalpinia sappan L.) toward the growth of A. actinomycetemcomitans and P. gingivalis. The randomized post test only control group design was applied to this study. The sappan wood ethanol extract was conducted with maceration method using 96% ethanol. Diluted to 50%, 25%, 12.5%, 6.25%, 3.125%, 1.56%, 0.78%, and 0.39% concentration. The MIC and MBC values of sappan wood ethanol extract toward A. actinomycetemcomitans and P. gingivalis was then known via the evaluation for Colony Forming Units (CFUs) In MH medium. The MIC and MBC of sappan wood ethanol extract toward A. actinomycetemcomitans and P. gingivalis was at 1.56% and 3.125% concentration. The ethanol extract of sappan wood reduces the number of bacterial colonies significantly at p=0.00. This study concluded that the growth of A. actinomycetemcomitans and P. gingivalis can be inhibited by sappan wood ethanol extract (Caesalpinia sappan L.) at MIC 1.56% and MBC 3.125% concentration.

Key words: Sappan wood ethanol extract, MIC 1.56%, MBC 3.125%, Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis..


 
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How to Cite this Article
Pubmed Style

Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti. Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. SRP. 2020; 11(3): 349-353. doi:10.5530/srp.2020.3.43


Web Style

Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti. Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. http://www.sysrevpharm.org//?mno=93389 [Access: April 04, 2020]. doi:10.5530/srp.2020.3.43


AMA (American Medical Association) Style

Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti. Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. SRP. 2020; 11(3): 349-353. doi:10.5530/srp.2020.3.43



Vancouver/ICMJE Style

Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti. Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. SRP. (2020), [cited April 04, 2020]; 11(3): 349-353. doi:10.5530/srp.2020.3.43



Harvard Style

Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti (2020) Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. SRP, 11 (3), 349-353. doi:10.5530/srp.2020.3.43



Turabian Style

Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti. 2020. Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. Systematic Reviews in Pharmacy, 11 (3), 349-353. doi:10.5530/srp.2020.3.43



Chicago Style

Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti. "Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis." Systematic Reviews in Pharmacy 11 (2020), 349-353. doi:10.5530/srp.2020.3.43



MLA (The Modern Language Association) Style

Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti. "Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis." Systematic Reviews in Pharmacy 11.3 (2020), 349-353. Print. doi:10.5530/srp.2020.3.43



APA (American Psychological Association) Style

Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti (2020) Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. Systematic Reviews in Pharmacy, 11 (3), 349-353. doi:10.5530/srp.2020.3.43





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