E-ISSN 0976-2779 | ISSN 0975-8453
 

Review Article 


Effect of Anti-Retroviral Fixed-Dose Combination Tenofovir, Lamivudine, And Evafirenz on Lipid Profile in HIV/AIDS Patients

Renny Anggraeni Puspitasari, Soebagijo Adi Soelistijo, Usman Hadi.

Abstract
Dyslipidemia has been recorded in antiretroviral therapy (HAART) naive HIV- and HAART HIV-patients. This study aimed to analyze the effect of Anti-Retroviral Fixed-Dose Combination (FDC) Tenofovir, Lamivudine, and Efavirenz on lipid profile in HIV/AIDS patients. This was a longitudinal observational study using one group pretest and posttest design. Subjects were measured for their lipid profile including total cholesterol, triglyceride, LDL, and HDL before and after 3 months receiving FDC ARV. Twenty subjects involved in this study. The mean total cholesterol before the treatment was 163.3026.38 mg/dl and after 3-month treatment 183.1526.36 mg/dl (p = 0.008). The mean of triglyceride before the treatment was 127.7527.57 mg/dl and after 3 months 154.1534.43 mg/dl (p = 0.003). The mean LDL before of the treatment was 92.9027.30 mg/dl and after 3 months 109.9522.49 mg/dl (p = 0.011) and mean of HDL before the treatment was 45.757.22 mg/dl and after 3 months 40.405.37 mg/dl (p = 0.003). FDC ARV had a significant effect on lipid profiles. Hence, a baseline lipid profile should be obtained in all HIV infected patients before and during antiretroviral treatment.

Key words: Teoritin, Dyslipidemia; total cholesterol, triglyceride, LDL; HDL, HIV-nave, anti-retrovirus


 
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How to Cite this Article
Pubmed Style

Renny Anggraeni Puspitasari, Soebagijo Adi Soelistijo, Usman Hadi. Effect of Anti-Retroviral Fixed-Dose Combination Tenofovir, Lamivudine, And Evafirenz on Lipid Profile in HIV/AIDS Patients. SRP. 2020; 11(3): 624-627. doi:10.31838/srp.2020.3.83


Web Style

Renny Anggraeni Puspitasari, Soebagijo Adi Soelistijo, Usman Hadi. Effect of Anti-Retroviral Fixed-Dose Combination Tenofovir, Lamivudine, And Evafirenz on Lipid Profile in HIV/AIDS Patients. http://www.sysrevpharm.org//?mno=96054 [Access: June 01, 2020]. doi:10.31838/srp.2020.3.83


AMA (American Medical Association) Style

Renny Anggraeni Puspitasari, Soebagijo Adi Soelistijo, Usman Hadi. Effect of Anti-Retroviral Fixed-Dose Combination Tenofovir, Lamivudine, And Evafirenz on Lipid Profile in HIV/AIDS Patients. SRP. 2020; 11(3): 624-627. doi:10.31838/srp.2020.3.83



Vancouver/ICMJE Style

Renny Anggraeni Puspitasari, Soebagijo Adi Soelistijo, Usman Hadi. Effect of Anti-Retroviral Fixed-Dose Combination Tenofovir, Lamivudine, And Evafirenz on Lipid Profile in HIV/AIDS Patients. SRP. (2020), [cited June 01, 2020]; 11(3): 624-627. doi:10.31838/srp.2020.3.83



Harvard Style

Renny Anggraeni Puspitasari, Soebagijo Adi Soelistijo, Usman Hadi (2020) Effect of Anti-Retroviral Fixed-Dose Combination Tenofovir, Lamivudine, And Evafirenz on Lipid Profile in HIV/AIDS Patients. SRP, 11 (3), 624-627. doi:10.31838/srp.2020.3.83



Turabian Style

Renny Anggraeni Puspitasari, Soebagijo Adi Soelistijo, Usman Hadi. 2020. Effect of Anti-Retroviral Fixed-Dose Combination Tenofovir, Lamivudine, And Evafirenz on Lipid Profile in HIV/AIDS Patients. Systematic Reviews in Pharmacy, 11 (3), 624-627. doi:10.31838/srp.2020.3.83



Chicago Style

Renny Anggraeni Puspitasari, Soebagijo Adi Soelistijo, Usman Hadi. "Effect of Anti-Retroviral Fixed-Dose Combination Tenofovir, Lamivudine, And Evafirenz on Lipid Profile in HIV/AIDS Patients." Systematic Reviews in Pharmacy 11 (2020), 624-627. doi:10.31838/srp.2020.3.83



MLA (The Modern Language Association) Style

Renny Anggraeni Puspitasari, Soebagijo Adi Soelistijo, Usman Hadi. "Effect of Anti-Retroviral Fixed-Dose Combination Tenofovir, Lamivudine, And Evafirenz on Lipid Profile in HIV/AIDS Patients." Systematic Reviews in Pharmacy 11.3 (2020), 624-627. Print. doi:10.31838/srp.2020.3.83



APA (American Psychological Association) Style

Renny Anggraeni Puspitasari, Soebagijo Adi Soelistijo, Usman Hadi (2020) Effect of Anti-Retroviral Fixed-Dose Combination Tenofovir, Lamivudine, And Evafirenz on Lipid Profile in HIV/AIDS Patients. Systematic Reviews in Pharmacy, 11 (3), 624-627. doi:10.31838/srp.2020.3.83