A Novel Synthesis, Molecular Structure by X-ray Diffraction of 5-Nitro-2,4,6-Triphenylhexahydropyrimidine, and Some it's Derivatives

Abstract

Shukkur A. Hamed.

A novel of the title compound and some its derivatives were synthesized in a good to excellent yields of seven derivatives, by condensation of three components: benzaldehyde or some various monosubstituted of its derivatives, ammonium acetate, and nitromethane with ratio 3:2:1 respectively, in presence n-butanol, by type Mannich reaction in one–pot. The products were characterized by FTIR, 1H NMR, and Mass spectroscopy. The molecular structure of 5-nitro-2,4,6-triphenylhexahydropyrimidine was affirmed by X-ray crystallography analysis of single-crystal.