A Study of The Effect of Aqueous and Alcoholic Extract of Saliva on The Reduction of Induced Hepatotoxicity in Laboratory Animals with Carbon Tetrachloride CCL4
Nuha Ali Hadi, Rabeah T.Mahmood.
The study aimed to know the effect of the aqueous and alcoholic extract of the Saliva plant on laboratory rats in which poisoning with carbon tetrachloride was introduced. It was divided into four groups. The first group represented the healthy control. Water and food were only given, while the disease- infected control was injected with protonate at a rate of 1 ml / kg / day for four weeks.
The third and fourth group injected protons with 1 ml / kg / day and an oral dose of 1 ml / kg / day of aqueous and alcoholic extract, respectively, for a period of four weeks. Biochemical tests were performed, urea and creatinine were measured, and there was a significant decrease in the disease- infected control compared to the healthy control and an increase compared to the aqueous and alcoholic extract group at a probability level of 0.05.
As for the total protein, uric acid, TC, TG, HDL, LDL, AST, ALT, a significant decrease was found in the aqueous and alcoholic extract groups at the probability level 0.05 compared to the infected control.