Analytical determination for chlorprothixene.HCl drug in pure form and medicinal tablets by spectrophotometric derivatives
Abstract
Aayad Ammar Sayhood, Bayan Jabr Hussein, Mohanad Hazim Halboos
Quantitative measurement, easy, accurate, and reproductive analysis of chlorprothixene.HCl medications (COT) using one of chemometrics method, the spectrophotometric derivatives method of zero (D0), first (D1) and second (D2) order. These suggested methods had been used to determine the (COT) between the range (0.4-3) μg.ml-1, 196.6 and 258.4 nm for 0th order; in (D1) range at 215.8, 247.2 and 268.4 nm; and in (D2) range derivative spectrophotometry at 223.2 and 257.4 nm, respectively. The precise and accurate results of the methods employed have been calculated and are very satisfactory. The limit of detection was estimated in this study, and it ranged between (0.0531-0.0611) μg.ml-1; As for the limit of quantification, it ranged between (0.1776-0.2044) μg.mL-1. This method has been applied to some medicinal doses consisting of this drug (COT), and the results have been impressive.
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| Pubmed Style Aayad Ammar Sayhood, Bayan Jabr Hussein, Mohanad Hazim Halboos. Analytical determination for chlorprothixene.HCl drug in pure form and medicinal tablets by spectrophotometric derivatives. SRP. 2020; 11(12): 1478-1482. doi:10.31838/srp.2020.12.219 Web Style Aayad Ammar Sayhood, Bayan Jabr Hussein, Mohanad Hazim Halboos. Analytical determination for chlorprothixene.HCl drug in pure form and medicinal tablets by spectrophotometric derivatives. http://www.sysrevpharm.org/?mno=16582 [Access: March 28, 2021]. doi:10.31838/srp.2020.12.219 AMA (American Medical Association) Style Aayad Ammar Sayhood, Bayan Jabr Hussein, Mohanad Hazim Halboos. Analytical determination for chlorprothixene.HCl drug in pure form and medicinal tablets by spectrophotometric derivatives. SRP. 2020; 11(12): 1478-1482. doi:10.31838/srp.2020.12.219 Vancouver/ICMJE Style Aayad Ammar Sayhood, Bayan Jabr Hussein, Mohanad Hazim Halboos. Analytical determination for chlorprothixene.HCl drug in pure form and medicinal tablets by spectrophotometric derivatives. SRP. (2020), [cited March 28, 2021]; 11(12): 1478-1482. doi:10.31838/srp.2020.12.219 Harvard Style Aayad Ammar Sayhood, Bayan Jabr Hussein, Mohanad Hazim Halboos (2020) Analytical determination for chlorprothixene.HCl drug in pure form and medicinal tablets by spectrophotometric derivatives. SRP, 11 (12), 1478-1482. doi:10.31838/srp.2020.12.219 Turabian Style Aayad Ammar Sayhood, Bayan Jabr Hussein, Mohanad Hazim Halboos. 2020. Analytical determination for chlorprothixene.HCl drug in pure form and medicinal tablets by spectrophotometric derivatives. Systematic Reviews in Pharmacy, 11 (12), 1478-1482. doi:10.31838/srp.2020.12.219 Chicago Style Aayad Ammar Sayhood, Bayan Jabr Hussein, Mohanad Hazim Halboos. "Analytical determination for chlorprothixene.HCl drug in pure form and medicinal tablets by spectrophotometric derivatives." Systematic Reviews in Pharmacy 11 (2020), 1478-1482. doi:10.31838/srp.2020.12.219 MLA (The Modern Language Association) Style Aayad Ammar Sayhood, Bayan Jabr Hussein, Mohanad Hazim Halboos. "Analytical determination for chlorprothixene.HCl drug in pure form and medicinal tablets by spectrophotometric derivatives." Systematic Reviews in Pharmacy 11.12 (2020), 1478-1482. Print. doi:10.31838/srp.2020.12.219 APA (American Psychological Association) Style Aayad Ammar Sayhood, Bayan Jabr Hussein, Mohanad Hazim Halboos (2020) Analytical determination for chlorprothixene.HCl drug in pure form and medicinal tablets by spectrophotometric derivatives. Systematic Reviews in Pharmacy, 11 (12), 1478-1482. doi:10.31838/srp.2020.12.219 |
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