Assessment the linking of Insulin-like growth factor 1 hormone and their gene polymorphism with excess adiposity

Abstract

Amera Kamal Mohammed, Chrow Ahmed Khurshid, Heman Burhanalden Abdulrahman.

This study aims to determine the correlation between the serum IGF-1 concentrations hormone and their gene polymorphism with excess adiposity (obese adults) in Babylon province. The study has performed on 50 participants divided into obese (n=30) and control (n=20) groups with age range (20-40 years). No significant differences have been reported in the concentrations of IGF-1 hormone in obese group. However, the results showed that genotype distribution of AA and AB in IGF-1 gene polymorphism was represented by 83.3% and 16.7%, respectively. While in control group, it was 90.0% and 10.0%, respectively. Furthermore, in obese group, the allele frequency of A and B in IGF-1 gene polymorphism was represented by 91.65% and 8.35%, respectively, whereas the control group presented as 95.0% and 5.0%, respectively. Moreover, several single nucleotide polymorphisms (SNPs) were obtained between the two resolved haplotypes and between the IGF1 genes. The results demonstrate that there is no association between AA and AB polymorphisms in the obese group (OR=0.87, CI [0.71-1.17]) as compared with the control group.

How to Cite this Article
Pubmed Style

Amera Kamal Mohammed, Chrow Ahmed Khurshid, Heman Burhanalden Abdulrahman. Assessment the linking of Insulin-like growth factor 1 hormone and their gene polymorphism with excess adiposity. SRP. 2020; 11(5): 649-653. 
doi:10.31838/srp.2020.5.91

Web Style

Amera Kamal Mohammed, Chrow Ahmed Khurshid, Heman Burhanalden Abdulrahman. Assessment the linking of Insulin-like growth factor 1 hormone and their gene polymorphism with excess adiposity. http://www.sysrevpharm.org/?mno=113366 [Access: March 30, 2021]. doi:10.31838/srp.2020.5.91

AMA (American Medical Association) Style

Amera Kamal Mohammed, Chrow Ahmed Khurshid, Heman Burhanalden Abdulrahman. Assessment the linking of Insulin-like growth factor 1 hormone and their gene polymorphism with excess adiposity. SRP. 2020; 11(5): 649-653. doi:10.31838/srp.2020.5.91



Vancouver/ICMJE Style

Amera Kamal Mohammed, Chrow Ahmed Khurshid, Heman Burhanalden Abdulrahman. Assessment the linking of Insulin-like growth factor 1 hormone and their gene polymorphism with excess adiposity. SRP. (2020), [cited March 30, 2021]; 11(5): 649-653. doi:10.31838/srp.2020.5.91



Harvard Style

Amera Kamal Mohammed, Chrow Ahmed Khurshid, Heman Burhanalden Abdulrahman (2020) Assessment the linking of Insulin-like growth factor 1 hormone and their gene polymorphism with excess adiposity. SRP, 11 (5), 649-653. doi:10.31838/srp.2020.5.91



Turabian Style

Amera Kamal Mohammed, Chrow Ahmed Khurshid, Heman Burhanalden Abdulrahman. 2020. Assessment the linking of Insulin-like growth factor 1 hormone and their gene polymorphism with excess adiposity. Systematic Reviews in Pharmacy, 11 (5), 649-653. doi:10.31838/srp.2020.5.91



Chicago Style

Amera Kamal Mohammed, Chrow Ahmed Khurshid, Heman Burhanalden Abdulrahman. "Assessment the linking of Insulin-like growth factor 1 hormone and their gene polymorphism with excess adiposity." Systematic Reviews in Pharmacy 11 (2020), 649-653. doi:10.31838/srp.2020.5.91



MLA (The Modern Language Association) Style

Amera Kamal Mohammed, Chrow Ahmed Khurshid, Heman Burhanalden Abdulrahman. "Assessment the linking of Insulin-like growth factor 1 hormone and their gene polymorphism with excess adiposity." Systematic Reviews in Pharmacy 11.5 (2020), 649-653. Print. doi:10.31838/srp.2020.5.91



APA (American Psychological Association) Style

Amera Kamal Mohammed, Chrow Ahmed Khurshid, Heman Burhanalden Abdulrahman (2020) Assessment the linking of Insulin-like growth factor 1 hormone and their gene polymorphism with excess adiposity. Systematic Reviews in Pharmacy, 11 (5), 649-653. doi:10.31838/srp.2020.5.91

 

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