Clinical Outcomes of Stem Cell Metabolites Formula Derived from Placenta for Skin Regeneration
Abstract
Purwati, Afif Nurul H, M. Yulianto Listiawan, Ernawati, Fedik A. Rantam, Medhi Denisa A, Novianti Risky R, Ardhiah Iswanda P, Imam Susilo, Diah Puspita R, Afriyanti Sandhi, Prasasta Adhistana.
Background: Previous research focused on in vitro and animal study of stem cell metabolites formula derived from the placenta for skin regeneration.
Objective: This further study is a clinical trial to evaluate the effectiveness of stem cell metabolites formula in skin regeneration.
Methods: Priorly, subjects’ facial conditions were examined and recorded using Janus skin analyzer to observe marks and blemishes present on their skin. Stem cell metabolites were applied on the face twice a day, day and night, with single-use doses of three pumps. We evaluated before and after stem cell metabolites application using Janus over the period six months, with three times repeated evaluation every two months. The Janus evaluation results are Spot, Pore, Roughness, Wrinkle, UV Acne, UV Spot, and UV Moisture.
Results: The percentage of spot, pore, roughness, wrinkle, UV acne, and UV spots were noticeably reduced. Meanwhile, the percentage of UV moisture increased in almost all subjects who were evaluated for six months. From a qualitative aspect, 90% of subjects are satisfied with the results of the application of stem cell metabolites. The subjects felt that facial wrinkles had reduced, the face was smoother and supple, and reduction in dark pigmentation.
Conclusion: It can be concluded that stem cell metabolites are useful in face skin regeneration.
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| Pubmed Style Purwati, Afif Nurul H, M. Yulianto Listiawan, Ernawati, Fedik A. Rantam, Medhi Denisa A, Novianti Risky R, Ardhiah Iswanda P, Imam Susilo, Diah Puspita R, Afriyanti Sandhi, Prasasta Adhistana. Clinical Outcomes of Stem Cell Metabolites Formula Derived from Placenta for Skin Regeneration. SRP. 2020; 11(5): 768-771. doi:10.31838/srp.2020.5.111 Web Style Purwati, Afif Nurul H, M. Yulianto Listiawan, Ernawati, Fedik A. Rantam, Medhi Denisa A, Novianti Risky R, Ardhiah Iswanda P, Imam Susilo, Diah Puspita R, Afriyanti Sandhi, Prasasta Adhistana. Clinical Outcomes of Stem Cell Metabolites Formula Derived from Placenta for Skin Regeneration. http://www.sysrevpharm.org/?mno=127002 [Access: March 29, 2021]. doi:10.31838/srp.2020.5.111 AMA (American Medical Association) Style Purwati, Afif Nurul H, M. Yulianto Listiawan, Ernawati, Fedik A. Rantam, Medhi Denisa A, Novianti Risky R, Ardhiah Iswanda P, Imam Susilo, Diah Puspita R, Afriyanti Sandhi, Prasasta Adhistana. Clinical Outcomes of Stem Cell Metabolites Formula Derived from Placenta for Skin Regeneration. SRP. 2020; 11(5): 768-771. doi:10.31838/srp.2020.5.111 Vancouver/ICMJE Style Purwati, Afif Nurul H, M. Yulianto Listiawan, Ernawati, Fedik A. Rantam, Medhi Denisa A, Novianti Risky R, Ardhiah Iswanda P, Imam Susilo, Diah Puspita R, Afriyanti Sandhi, Prasasta Adhistana. Clinical Outcomes of Stem Cell Metabolites Formula Derived from Placenta for Skin Regeneration. SRP. (2020), [cited March 29, 2021]; 11(5): 768-771. doi:10.31838/srp.2020.5.111 Harvard Style Purwati, Afif Nurul H, M. Yulianto Listiawan, Ernawati, Fedik A. Rantam, Medhi Denisa A, Novianti Risky R, Ardhiah Iswanda P, Imam Susilo, Diah Puspita R, Afriyanti Sandhi, Prasasta Adhistana (2020) Clinical Outcomes of Stem Cell Metabolites Formula Derived from Placenta for Skin Regeneration. SRP, 11 (5), 768-771. doi:10.31838/srp.2020.5.111 Turabian Style Purwati, Afif Nurul H, M. Yulianto Listiawan, Ernawati, Fedik A. Rantam, Medhi Denisa A, Novianti Risky R, Ardhiah Iswanda P, Imam Susilo, Diah Puspita R, Afriyanti Sandhi, Prasasta Adhistana. 2020. Clinical Outcomes of Stem Cell Metabolites Formula Derived from Placenta for Skin Regeneration. Systematic Reviews in Pharmacy, 11 (5), 768-771. doi:10.31838/srp.2020.5.111 Chicago Style Purwati, Afif Nurul H, M. Yulianto Listiawan, Ernawati, Fedik A. Rantam, Medhi Denisa A, Novianti Risky R, Ardhiah Iswanda P, Imam Susilo, Diah Puspita R, Afriyanti Sandhi, Prasasta Adhistana. "Clinical Outcomes of Stem Cell Metabolites Formula Derived from Placenta for Skin Regeneration." Systematic Reviews in Pharmacy 11 (2020), 768-771. doi:10.31838/srp.2020.5.111 MLA (The Modern Language Association) Style Purwati, Afif Nurul H, M. Yulianto Listiawan, Ernawati, Fedik A. Rantam, Medhi Denisa A, Novianti Risky R, Ardhiah Iswanda P, Imam Susilo, Diah Puspita R, Afriyanti Sandhi, Prasasta Adhistana. "Clinical Outcomes of Stem Cell Metabolites Formula Derived from Placenta for Skin Regeneration." Systematic Reviews in Pharmacy 11.5 (2020), 768-771. Print. doi:10.31838/srp.2020.5.111 APA (American Psychological Association) Style Purwati, Afif Nurul H, M. Yulianto Listiawan, Ernawati, Fedik A. Rantam, Medhi Denisa A, Novianti Risky R, Ardhiah Iswanda P, Imam Susilo, Diah Puspita R, Afriyanti Sandhi, Prasasta Adhistana (2020) Clinical Outcomes of Stem Cell Metabolites Formula Derived from Placenta for Skin Regeneration. Systematic Reviews in Pharmacy, 11 (5), 768-771. doi:10.31838/srp.2020.5.111 |
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