Current Therapies and Novel Targets in Treatment of Breast Cancer

Abstract

Kaur H, Saini S, Peer S, Singh J

Breast cancer is the most common cause of cancer-related death among women worldwide, with case fatality rates highest in low-resource countries. Despite significant scientific advances in its management, most of the world faces resource constraints that limit the capacity to improve early detection, diagnosis, and treatment of the disease. There are different types of breast cancer, and different treatments that can work for each. Breast cancer is a highly complex disease with many treatment options including surgery, radiotherapy, hormonal therapy, biological therapy and chemotherapy. Optimizing standard treatment modalities for breast cancer has improved the outlook for women afflicted with it, but the fact that 40% still ultimately die from the disease highlights the need for new therapies. Remarkable advances in molecular immunology and biotechnology have created a unique opportunity for developing active vaccination strategies that engage the patient’s own immune system in the fight against breast cancer. This article will review current drugs used in treatment of breast cancer and the novel targets which will be used safe and effective management of breast cancer.