CYP24A1 and AHR Gene Expression in Iraqi Colorectal Cancer Patients
Abstract
Wathiq Abbas Aldrghi, Alaa Makki Jabbar Shafeea, Nawal Mehdi Alkhalidi.
Previous studies indicated colorectal cancer (CRC) is the third leading cause of cancer in the world and the second in terms of mortality , CRC is spread between men and women , CRC spreads in different location of the colon and rectum, . Colorectal cancer affects in different age and the number of CRC patient has increased in the past two decades, especially within the younger age. Molecular studies indicated, many changes in genetic, epigenetic and gene expression in many genes contributed to the emergence and development of colorectal cancer. This study aimed to measure the gene expression for CYP24A1 and AHR genes in iraqi patients with CRC, and study age groups and locations of CRC within the colon and rectum. The results showed an overexpression of CYP24A1 gene (6.1) fold change and AHR expression had(1.8) fold change ,and males are more likely to develop colon rectal cancer than women's, and most patient colorectal cancer ranged between 45 to 68 years old .
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| Pubmed Style Aldrghi WA, Shafeea AMJ, Alkhalidi NM. CYP24A1 and AHR Gene Expression in Iraqi Colorectal Cancer Patients. SRP. 2020; 11(9): 89-94. doi:10.31838/srp.2020.9.15 Web Style Aldrghi WA, Shafeea AMJ, Alkhalidi NM. CYP24A1 and AHR Gene Expression in Iraqi Colorectal Cancer Patients. http://www.sysrevpharm.org/?mno=138319 [Access: March 29, 2021]. doi:10.31838/srp.2020.9.15 AMA (American Medical Association) Style Aldrghi WA, Shafeea AMJ, Alkhalidi NM. CYP24A1 and AHR Gene Expression in Iraqi Colorectal Cancer Patients. SRP. 2020; 11(9): 89-94. doi:10.31838/srp.2020.9.15 Vancouver/ICMJE Style Aldrghi WA, Shafeea AMJ, Alkhalidi NM. CYP24A1 and AHR Gene Expression in Iraqi Colorectal Cancer Patients. SRP. (2020), [cited March 29, 2021]; 11(9): 89-94. doi:10.31838/srp.2020.9.15 Harvard Style Aldrghi, W. A., Shafeea, . A. M. J. & Alkhalidi, . N. M. (2020) CYP24A1 and AHR Gene Expression in Iraqi Colorectal Cancer Patients. SRP, 11 (9), 89-94. doi:10.31838/srp.2020.9.15 Turabian Style Aldrghi, Wathiq Abbas, Alaa Makki Jabbar Shafeea, and Nawal Mehdi Alkhalidi. 2020. CYP24A1 and AHR Gene Expression in Iraqi Colorectal Cancer Patients. Systematic Reviews in Pharmacy, 11 (9), 89-94. doi:10.31838/srp.2020.9.15 Chicago Style Aldrghi, Wathiq Abbas, Alaa Makki Jabbar Shafeea, and Nawal Mehdi Alkhalidi. "CYP24A1 and AHR Gene Expression in Iraqi Colorectal Cancer Patients." Systematic Reviews in Pharmacy 11 (2020), 89-94. doi:10.31838/srp.2020.9.15 MLA (The Modern Language Association) Style Aldrghi, Wathiq Abbas, Alaa Makki Jabbar Shafeea, and Nawal Mehdi Alkhalidi. "CYP24A1 and AHR Gene Expression in Iraqi Colorectal Cancer Patients." Systematic Reviews in Pharmacy 11.9 (2020), 89-94. Print. doi:10.31838/srp.2020.9.15 APA (American Psychological Association) Style Aldrghi, W. A., Shafeea, . A. M. J. & Alkhalidi, . N. M. (2020) CYP24A1 and AHR Gene Expression in Iraqi Colorectal Cancer Patients. Systematic Reviews in Pharmacy, 11 (9), 89-94. doi:10.31838/srp.2020.9.15 |
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