Estimation The Trace Elements And Their Association With Insulin Resistance In Obese Adults.

Abstract

Fadil A. Al-Quraishe, Ahamad T. Ghadhban.

Background: Trace elements are essential micronutrients in the development of the metabolic complication of obesity , arterial hypertension ,dyslipidemia , and insulin resistance or diabetes . According these it is important to known and measure the trace elements status in obesity.
Aim of the study: A study was performed to estimate serum levels trace elements status Sodium( Na) , Potassium (K ) , Calcium (Ca ) ,and, Chloride (Cl )in the adults obese comparison with normal weight controls , and to evaluate their potential association with insulin resistance .
Material and Methods: Eighty obesity with Body Mass Index(BMI) 35-39.5 Kg/m2and twenty health person with ( BMI ) 18 -24.5 Kg/m2 as control group aged 20-40 years were assessed the serum levels trace elements and also were evaluated the insulin resistance in the obesity and control groups, according to Homeo- static Model Of Assessment for Insulin Resistance (HOMA-IR) protocol.
Results : Compared to the control group Ca and K serum levels were significantly lower ( all P<0.05 ) and Na and Cl serum levels were significantly higher (P< 0.05 ) in the adults obese group in all age groups . Also significant inverse correlation was found between HOMA-IR and Ca level.
Conclusion : Obesity adults have higher mineral serum levels especially Na and Cl than control group in all age groups, and lower Ca and K which contributed with insulin resistance.