Evaluation of IL-1 and IL-10 Concentration Level in Study of Epstein Barr Virus that Detected in Patients Suffered from Stomach Cancer in Al Hilla City

Abstract

Haneen Hussein Abd Al-ridha, Humam Kasem Hussein

Objective: The current research was conducted to determine the concentration level of IL-1 and IL-10 in Patients Suffered from Stomach Cancer infection.
Methodology: Descriptive case-control study design, the present study was conducted on 75 patients (56 males and 19 females) attended to, AL-Margan Hospital and AL-Sader Hospital in Hilla city from September, to November 2019. The patients were diagnosed clinically by physicians, who suffered from Stomach Cancer. In addition to that, a control group of 75 apparently healthy individuals (59 males and 16 females) who were without any history of disease were included.
Results: Individuals with EBV infection were found to have positive association with Stomach Cancer (18.7) in age groups(48-39 )years.
Evaluation of immune status among EBV patients infected with Stomach Cancer through measuring the study showed a significant increase in the level of IL-1 and IL-10 among the clinical study groups. The study showed a significant increase at (P-value = 0.001) in IL-1 concentration (16.8 ± 4.6) in the age group (<59) compared to the control group (4.1 ± 2.1).This study also found that the concentration of Interleukin 10 showed a significant increase (188.1 ± 154.1) at (P- value = 0.01) in the age group (49-53) years compared to the control group (6.2 ± 0.3).