Human Leukocyte Antigen (HLA-G) Expression and Soluble HLA-G Levels in Women with Breast Cancer from Basrah Province in Iraq
Abstract
Hadeel Saleem Touma, Wafaa Sadoon Shani, Talaat Sadoon Shani
HLA-G is one of the non-classical HLA class I molecules and it is known to be implicated in a tumor-driven immune escape mechanism in malignancy. The purpose of this study was to investigate soluble HLA-G (sHLA-G) and HLA-G expression in breast cancer. sHLA-G was determined by enzyme-linked Immunosorbent assay (ELISA) from plasma samples of 70 breast cancer patients and 35 healthy controls. HLA-G expression in breast cancer lesions was also analyzed by immunohistochemistry staining. The presence of HLA-G expression were analyzed and found to be involved in breast carcinogenesis. Levels of sHLA-G were higher in the breast cancer group compared to the control group and sHLA-G concentration could be used as a diagnostic marker for detecting breast cancer.
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| Pubmed Style Hadeel Saleem Touma, Wafaa Sadoon Shani, Talaat Sadoon Shani. Human Leukocyte Antigen (HLA-G) Expression and Soluble HLA-G Levels in Women with Breast Cancer from Basrah Province in Iraq. SRP. 2020; 11(6): 871-877. doi:10.31838srp.2020.6.125 Web Style Hadeel Saleem Touma, Wafaa Sadoon Shani, Talaat Sadoon Shani. Human Leukocyte Antigen (HLA-G) Expression and Soluble HLA-G Levels in Women with Breast Cancer from Basrah Province in Iraq. http://www.sysrevpharm.org/?mno=9935 [Access: March 29, 2021]. doi:10.31838srp.2020.6.125 AMA (American Medical Association) Style Hadeel Saleem Touma, Wafaa Sadoon Shani, Talaat Sadoon Shani. Human Leukocyte Antigen (HLA-G) Expression and Soluble HLA-G Levels in Women with Breast Cancer from Basrah Province in Iraq. SRP. 2020; 11(6): 871-877. doi:10.31838srp.2020.6.125 Vancouver/ICMJE Style Hadeel Saleem Touma, Wafaa Sadoon Shani, Talaat Sadoon Shani. Human Leukocyte Antigen (HLA-G) Expression and Soluble HLA-G Levels in Women with Breast Cancer from Basrah Province in Iraq. SRP. (2020), [cited March 29, 2021]; 11(6): 871-877. doi:10.31838srp.2020.6.125 Harvard Style Hadeel Saleem Touma, Wafaa Sadoon Shani, Talaat Sadoon Shani (2020) Human Leukocyte Antigen (HLA-G) Expression and Soluble HLA-G Levels in Women with Breast Cancer from Basrah Province in Iraq. SRP, 11 (6), 871-877. doi:10.31838srp.2020.6.125 Turabian Style Hadeel Saleem Touma, Wafaa Sadoon Shani, Talaat Sadoon Shani. 2020. Human Leukocyte Antigen (HLA-G) Expression and Soluble HLA-G Levels in Women with Breast Cancer from Basrah Province in Iraq. Systematic Reviews in Pharmacy, 11 (6), 871-877. doi:10.31838srp.2020.6.125 Chicago Style Hadeel Saleem Touma, Wafaa Sadoon Shani, Talaat Sadoon Shani. "Human Leukocyte Antigen (HLA-G) Expression and Soluble HLA-G Levels in Women with Breast Cancer from Basrah Province in Iraq." Systematic Reviews in Pharmacy 11 (2020), 871-877. doi:10.31838srp.2020.6.125 MLA (The Modern Language Association) Style Hadeel Saleem Touma, Wafaa Sadoon Shani, Talaat Sadoon Shani. "Human Leukocyte Antigen (HLA-G) Expression and Soluble HLA-G Levels in Women with Breast Cancer from Basrah Province in Iraq." Systematic Reviews in Pharmacy 11.6 (2020), 871-877. Print. doi:10.31838srp.2020.6.125 APA (American Psychological Association) Style Hadeel Saleem Touma, Wafaa Sadoon Shani, Talaat Sadoon Shani (2020) Human Leukocyte Antigen (HLA-G) Expression and Soluble HLA-G Levels in Women with Breast Cancer from Basrah Province in Iraq. Systematic Reviews in Pharmacy, 11 (6), 871-877. doi:10.31838srp.2020.6.125 |
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