Inflammatory Effect of Interleukin ? 6 and C ? Reactive Protein in Development of Stroke in Tikrit City

Abstract

Mohamed Ghalib Zakari, Bassam Taha Saleh, Muayad Khalaf Ibrahim

This study was conducted in Tikrit city for the period from February 1, 2018 to June 1, 2018, where the study included 50 patients with stroke who attended to Salah Al-Din general hospital in Tikrit city. The study also included 50 healthy subjects as control group. The study included the collection of 3 ml of venous blood for measurement of interleukin-6 by using ELISA technique (Koma-Biotech, Co, USA) and C-reactive protein. The study showed that the highest mean of IL-6 was recorded in patients under stroke (26.71±3.11 pg/ml) as compared with healthy control (11.18±2.21pg/ml) at P. value <0.01. The study showed that the maximum mean of CRP was recorded in patients under stroke (5.22±0.21 mg/dl) as compared with healthy control (1.01± 0.17 mg/dl) at P. value <0.01. The study significant relation of type of stroke with IL-6 and CRP levels as the highest mean levels of IL-6 and CRP were recorded in patients under severe stroke and the lowest mean were in patients under mild stroke (P<0.01).The study showed significant relation of IL-6 and CRP levels with stroke.

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