Is Hypertriglyceridemia a Key Detrimental Factor or Associative Triggering Factor for Cardiovascular Abnormalities?
Abstract
Pitchai Balakumar, Lalita Babbar, Sanjeev Kalra, Nanjaian Mahadevan, Seetharaman Sritharan, Pawan Krishan
Elevation of fasting plasma triglycerides above the normal level (150 mg/dL) is an indication of hypertriglyceridemia (borderline high, 150–199 mg/dL; high, 200-499 mg/dL; very high, above 500 mg/dL). A plethora of experimental and clinical studies evidenced a perceptible association between hypertriglyceridemia and cardiovascular disease. Hypertriglyceridmia could lead to endothelial dysfunction, atherosclerosis, hypertension, and ischemic heart disease. In addition, studies have demonstrated the myocardial susceptibility to ischemia-reperfusion injury in the hypertriglyceridemic condition. Importantly, hypertriglyceridemia alone may cause cardiovascular abnormalities like atherosclerosis even in absence of hypercholesterolemia. It is worth-mentioning that a pharmacological reduction in triglyceride levels diminishes the cardiovascular disease pathogenesis. It is a subject of contemporary interest to detail whether hypertriglyceridemia a key detrimental factor or an associative triggering factor for cardiovascular abnormalities. This review will discuss the potential role of hypertriglyceridemia in the pathogenesis of cardiovascular disorders.
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| Pubmed Style Pitchai Balakumar, Lalita Babbar, Sanjeev Kalra, Nanjaian Mahadevan, Seetharaman Sritharan, Pawan Krishan. Is Hypertriglyceridemia a Key Detrimental Factor or Associative Triggering Factor for Cardiovascular Abnormalities?. SRP. 2012; 3(1): 1-3. doi:10.4103/0975-8453.107127 Web Style Pitchai Balakumar, Lalita Babbar, Sanjeev Kalra, Nanjaian Mahadevan, Seetharaman Sritharan, Pawan Krishan. Is Hypertriglyceridemia a Key Detrimental Factor or Associative Triggering Factor for Cardiovascular Abnormalities?. http://www.sysrevpharm.org/?mno=302644594 [Access: March 28, 2021]. doi:10.4103/0975-8453.107127 AMA (American Medical Association) Style Pitchai Balakumar, Lalita Babbar, Sanjeev Kalra, Nanjaian Mahadevan, Seetharaman Sritharan, Pawan Krishan. Is Hypertriglyceridemia a Key Detrimental Factor or Associative Triggering Factor for Cardiovascular Abnormalities?. SRP. 2012; 3(1): 1-3. doi:10.4103/0975-8453.107127 Vancouver/ICMJE Style Pitchai Balakumar, Lalita Babbar, Sanjeev Kalra, Nanjaian Mahadevan, Seetharaman Sritharan, Pawan Krishan. Is Hypertriglyceridemia a Key Detrimental Factor or Associative Triggering Factor for Cardiovascular Abnormalities?. SRP. (2012), [cited March 28, 2021]; 3(1): 1-3. doi:10.4103/0975-8453.107127 Harvard Style Pitchai Balakumar, Lalita Babbar, Sanjeev Kalra, Nanjaian Mahadevan, Seetharaman Sritharan, Pawan Krishan (2012) Is Hypertriglyceridemia a Key Detrimental Factor or Associative Triggering Factor for Cardiovascular Abnormalities?. SRP, 3 (1), 1-3. doi:10.4103/0975-8453.107127 Turabian Style Pitchai Balakumar, Lalita Babbar, Sanjeev Kalra, Nanjaian Mahadevan, Seetharaman Sritharan, Pawan Krishan. 2012. Is Hypertriglyceridemia a Key Detrimental Factor or Associative Triggering Factor for Cardiovascular Abnormalities?. Systematic Reviews in Pharmacy, 3 (1), 1-3. doi:10.4103/0975-8453.107127 Chicago Style Pitchai Balakumar, Lalita Babbar, Sanjeev Kalra, Nanjaian Mahadevan, Seetharaman Sritharan, Pawan Krishan. "Is Hypertriglyceridemia a Key Detrimental Factor or Associative Triggering Factor for Cardiovascular Abnormalities?." Systematic Reviews in Pharmacy 3 (2012), 1-3. doi:10.4103/0975-8453.107127 MLA (The Modern Language Association) Style Pitchai Balakumar, Lalita Babbar, Sanjeev Kalra, Nanjaian Mahadevan, Seetharaman Sritharan, Pawan Krishan. "Is Hypertriglyceridemia a Key Detrimental Factor or Associative Triggering Factor for Cardiovascular Abnormalities?." Systematic Reviews in Pharmacy 3.1 (2012), 1-3. Print. doi:10.4103/0975-8453.107127 APA (American Psychological Association) Style Pitchai Balakumar, Lalita Babbar, Sanjeev Kalra, Nanjaian Mahadevan, Seetharaman Sritharan, Pawan Krishan (2012) Is Hypertriglyceridemia a Key Detrimental Factor or Associative Triggering Factor for Cardiovascular Abnormalities?. Systematic Reviews in Pharmacy, 3 (1), 1-3. doi:10.4103/0975-8453.107127is-hypertriglyceridemia-a-key-detrimental-factor-or-associative-triggering-factor-for-cardiovascular-abnormalities-64919.html |
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