Nanosponges as Emerging Carriers for Drug Delivery
Objective: The recent advancement in nanotechnology has led nanosponges to emerge as a suitable carrier for the delivery of both hydrophilic and lipophilic drugs. These are the tiny sponges that circulate throughout the body to achieve the desired dose of a drug in the specific organ of human bodies in a carefully controlled manner. They have higher drug loading capabilities as compared to other nanocarriers.
Methods: Nanosponges can also serve as a potent transporter for enzymes, proteins, and antibodies. This review attempts to elaborate on nanosponge’s merits and demerits, mechanism, composition, preparation, characterization, and their potential applications as delivery systems.
Conclusion: Nanosponges are a novel class of drug delivery systems as they treat both hydrophilic and hydrophobic drugs by forming inclusion and non-inclusion complexes. This nano technology provides beneficial effects that improve stability, reduce side effects and improve flexibility.