New mixed ligand complexes of New Schiff base 4,4'-((naphthalen-1-ylimino) methylene) dibenzene-1,3-diol and 8-hydroxy quinoline: Synthesis, Spectral Characterization, Thermal studies and Biological Activities

Abstract

Eman Mutar Atiyah, Wasan Mohammed Alwan, Hiyam Hadi Alkam

A new bidentate Schiff base ligand has been synthesized with the use of 2,2,4,4-tetrahydroxybenzophenone and1-naphthylamine. Its mixed ligand complexes of (MAQ) types [M= Mn (II),Co(II),Cu(II),Zn(II),Cd(II)and Hg(II); (HA)=Schiff base and (HQ)=8-hydroxy quinoline] . Ligand (HA) and complexes have been identified with the spectroscopic and analytical analyses including; micro-analysis, thermal analyses, chloride content, conductance, magnetic susceptibility for complexes, UV-Visible, FTIR, and 1H,13C-NMR spectroscopy. The physico-chemical methods indicated the complexes which have been shown 4 and 6 coordinate structures in solution and solid states. The ligand (HA) binds with the ions of M(II) through azomethine and de-protonated phenolic group and ligand (HQ) binds via the azomethine in the ring and de-protonated phenolic group. Thermal analysis was used to confirm the existence of coordination H2O molecule in complexes structure. According to mentioned characterization methods, Mixed ligand complexes of bivalent ion of Mn(II), Co(II), Cu(II), Zn(II), Cd(II) and Hg(II) of the according to formula [M(A)(Q)] in which [M= Mn(II),Zn(II),Cd(II)and Hg(II)] and the formula [M(A)(Q)(H2O)2] in which [M= Co(II)and Cu(II)] in (1:1:1) of molar ratio. In vitro biological free ligand (HA) activities, 8-hydroxy quinoline (HQ) and their metal complexes were observed for bacteria, E. coli and S. aureus by well diffusion technique.