Potency of Herbal Plants Formulation as Anticholesterole agent: In Vitro Studies

Abstract

Retno Widyani

Natural materials have excellent prospects in the field of health and beauty. The use of chemicals in the field of health and beauty has negative impacts. Indonesia is an extraordinarily rich country of natural materials. Natural materials that can be used include fruit, leaves, tubers, wood, fish, and animals. These natural ingredients are also called herbs. Herbal Plants used in traditional medicine in Indonesian to decrease cholesterol. Two herbal plant formulation used in this experiment. Formula A : Andropogus paniculata (35%), Piper battle (25%), Zingiber officinale (25%), Myrista fragrans (15%) and formula B : Dyospora kaki (50%), Apium grafeolens (20%), Guazuma uilmifollia (20%), Hisbiscus sabdarifa (10%). Control used green coconut water. The aim of the study determine the potency of this herbal formulation used in vitro methods. Cholesterol blood liquid made from isotonic liquid, calcium and yellow eggs similar to cholesterol content in blood 200 mg/dl. Formula herbal plant used 20 mg/dl, 40 mg/dl, and 60 mg/dl. Control used green coconut water. Proximate analysis used SNI methods and cholesterol analysis worked on the Centre of Agro-Based Industry Bogor used MU/INST/4 (GC) methods.The result of this experiment showed the major ingredient of proximate analysis is carbohydrate. Average cholesterol level in formula A decrease from 200 ml/dl to 23.3 mg/dl. In Formula B, cholesterol level decreased from 200 mg/dl to 86.9 mg/dl. Average cholesterol content in control 130.7 mg/dl. The study suggests that herbal plants formulation potential to decrease cholesterol