Quality of life among patients with Parkinson?s disease: A cross-sectional study in Vietnam
Abstract
Xuan Minh Ngo, Tram Thi Huyen Nguyen, Truc Thi Thanh Nguyen, Lam Ngoc Giang Doan, Nhan Thanh Ngo, Truong Vu Lam, Thoai Dang Nguyen*
Background: Health-related quality of life (HRQoL) is an important indicator of treatment outcomes for patients with Parkinson’s disease (PD). Accordingly, this study determined the HRQoL of PD patients in the context of Vietnam and explored whether disease duration and disease stage affect the HRQoL of the Vietnamese subjects.Methods: The research assessed 268 PD patients whose conditions have had a mean duration of 8.46 years. Among them, 139 (51.87%) additionally suffered from motor fluctuations and/or dyskinesia. The evaluation was conducted using the 39-item Parkinson’s Disease Questionnaire (PDQ-39), which consists of eight dimensions that can be scored from 0 to 100. The higher the score, the worse the QoL of a patient. Results: The comparison of the groups with and without motor fluctuations showed that the former scored higher in terms of mobility (MOB), activities of daily living (ADL), emotional well-being (EMO), stigma (STI), social support (SOC), and cognition (COG). A trend observed in this work was that high Hoehn and Yahr scores resulted in equally high PDQ-39 scores, except for the EMO and STI dimensions. The patients suffering fromthe disease for more than 5 years had worse MOB, ADL, STI, SOC, and COG scores than those of the subjects grappling with PD for ≤5 years. Conclusion: The PDQ-39 can determine a decrease in the QoL of PD patients, and such reduction is predicted by the occurrence of motor fluctuations.
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| Pubmed Style Ngo XM, Nguyen TTH, Nguyen TTT, Doan LNG, Ngo NT, Lam TV, Nguyen TD. Quality of life among patients with Parkinson’s disease: A cross-sectional study in Vietnam. SRP. 2019; 10(2): 8-14. doi:10.5530/srp.2019.2.02 Web Style Ngo XM, Nguyen TTH, Nguyen TTT, Doan LNG, Ngo NT, Lam TV, Nguyen TD. Quality of life among patients with Parkinson’s disease: A cross-sectional study in Vietnam. http://www.sysrevpharm.org/?mno=302644899 [Access: March 31, 2021]. doi:10.5530/srp.2019.2.02 AMA (American Medical Association) Style Ngo XM, Nguyen TTH, Nguyen TTT, Doan LNG, Ngo NT, Lam TV, Nguyen TD. Quality of life among patients with Parkinson’s disease: A cross-sectional study in Vietnam. SRP. 2019; 10(2): 8-14. doi:10.5530/srp.2019.2.02 Vancouver/ICMJE Style Ngo XM, Nguyen TTH, Nguyen TTT, Doan LNG, Ngo NT, Lam TV, Nguyen TD. Quality of life among patients with Parkinson’s disease: A cross-sectional study in Vietnam. SRP. (2019), [cited March 31, 2021]; 10(2): 8-14. doi:10.5530/srp.2019.2.02 Harvard Style Ngo, X. M., Nguyen, . T. T. H., Nguyen, . T. T. T., Doan, . L. N. G., Ngo, . N. T., Lam, . T. V. & Nguyen, . T. D. (2019) Quality of life among patients with Parkinson’s disease: A cross-sectional study in Vietnam. SRP, 10 (2), 8-14. doi:10.5530/srp.2019.2.02 Turabian Style Ngo, Xuan Minh, Tram Thi Huyen Nguyen, Truc Thi Thanh Nguyen, Lam Ngoc Giang Doan, Nhan Thanh Ngo, Truong Vu Lam, and Thoai Dang Nguyen. 2019. Quality of life among patients with Parkinson’s disease: A cross-sectional study in Vietnam. Systematic Reviews in Pharmacy, 10 (2), 8-14. doi:10.5530/srp.2019.2.02 Chicago Style Ngo, Xuan Minh, Tram Thi Huyen Nguyen, Truc Thi Thanh Nguyen, Lam Ngoc Giang Doan, Nhan Thanh Ngo, Truong Vu Lam, and Thoai Dang Nguyen. "Quality of life among patients with Parkinson’s disease: A cross-sectional study in Vietnam." Systematic Reviews in Pharmacy 10 (2019), 8-14. doi:10.5530/srp.2019.2.02 MLA (The Modern Language Association) Style Ngo, Xuan Minh, Tram Thi Huyen Nguyen, Truc Thi Thanh Nguyen, Lam Ngoc Giang Doan, Nhan Thanh Ngo, Truong Vu Lam, and Thoai Dang Nguyen. "Quality of life among patients with Parkinson’s disease: A cross-sectional study in Vietnam." Systematic Reviews in Pharmacy 10.2 (2019), 8-14. Print. doi:10.5530/srp.2019.2.02 APA (American Psychological Association) Style Ngo, X. M., Nguyen, . T. T. H., Nguyen, . T. T. T., Doan, . L. N. G., Ngo, . N. T., Lam, . T. V. & Nguyen, . T. D. (2019) Quality of life among patients with Parkinson’s disease: A cross-sectional study in Vietnam. Systematic Reviews in Pharmacy, 10 (2), 8-14. doi:10.5530/srp.2019.2.02 |
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