Reflections of the Anti-inflammatory Properties of Aspirin on Cardiovascular Disease and Diabetes Mellitus-related Pathological Markers
Abstract
Hind Makki Abdlwahid, Majid Mohammed Mahmood, Asaad F. Albayati.
To keep track of immune modulating effects of using prophylactic acetylsalicylic acid (ASA) or aspirin in Iraqi community, 60 selected patients taking aspirin were divided into two groups, depending on their medical conditions, group I (30 patient having cardiovascular disease), group II (30 patient having diabetes mellitus), versus 20 matched corresponding patients, don’t take aspirin, who were depended as control groups (ten each). All were tested for their inflammatory markers including levels of interleukin-1β (IL-1β), interleukin 6 (IL6) and high sensitivity C-reactive protein (hsCRP) by using ELIZA technique. Results recorded decreased levels of IL1β (0.357±0.03pg/ml), and IL6 (2.22 ±0.26pg/ml) in group I and (0.250 ± 0.02pg/ml) (1.450 ± 0.22pg/ml) in group II, compared to their counterparts of controls (5.31±1.29pg/ml) (12.66±1.46pg/ml), and (5.58±1.29pg/ml) (7.63±0.75pg/ml) in succession. Such results indicate the beneficial immune regulatory action of aspirin in cardiovascular and diabetic patients. Rather hsCRP showed no significant variations in both groups of patients compared to their controls; (4.039±0.29ng/ml vs 3.290±0.65ng/ml) and (5.06 ± 0.40ng/ml vs 6.29±0.54 ng/ml), respectively.
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| Pubmed Style Abdlwahid HM, Mahmood MM, Albayati AF. Reflections of the Anti-inflammatory Properties of Aspirin on Cardiovascular Disease and Diabetes Mellitus-related Pathological Markers. SRP. 2020; 11(7): 393-395. doi:10.31838/srp.2020.7.58 Web Style Abdlwahid HM, Mahmood MM, Albayati AF. Reflections of the Anti-inflammatory Properties of Aspirin on Cardiovascular Disease and Diabetes Mellitus-related Pathological Markers. http://www.sysrevpharm.org/?mno=127985 [Access: March 28, 2021]. doi:10.31838/srp.2020.7.58 AMA (American Medical Association) Style Abdlwahid HM, Mahmood MM, Albayati AF. Reflections of the Anti-inflammatory Properties of Aspirin on Cardiovascular Disease and Diabetes Mellitus-related Pathological Markers. SRP. 2020; 11(7): 393-395. doi:10.31838/srp.2020.7.58 Vancouver/ICMJE Style Abdlwahid HM, Mahmood MM, Albayati AF. Reflections of the Anti-inflammatory Properties of Aspirin on Cardiovascular Disease and Diabetes Mellitus-related Pathological Markers. SRP. (2020), [cited March 28, 2021]; 11(7): 393-395. doi:10.31838/srp.2020.7.58 Harvard Style Abdlwahid, H. M., Mahmood, . M. M. & Albayati, . A. F. (2020) Reflections of the Anti-inflammatory Properties of Aspirin on Cardiovascular Disease and Diabetes Mellitus-related Pathological Markers. SRP, 11 (7), 393-395. doi:10.31838/srp.2020.7.58 Turabian Style Abdlwahid, Hind Makki, Majid Mohammed Mahmood, and Asaad F. Albayati. 2020. Reflections of the Anti-inflammatory Properties of Aspirin on Cardiovascular Disease and Diabetes Mellitus-related Pathological Markers. Systematic Reviews in Pharmacy, 11 (7), 393-395. doi:10.31838/srp.2020.7.58 Chicago Style Abdlwahid, Hind Makki, Majid Mohammed Mahmood, and Asaad F. Albayati. "Reflections of the Anti-inflammatory Properties of Aspirin on Cardiovascular Disease and Diabetes Mellitus-related Pathological Markers." Systematic Reviews in Pharmacy 11 (2020), 393-395. doi:10.31838/srp.2020.7.58 MLA (The Modern Language Association) Style Abdlwahid, Hind Makki, Majid Mohammed Mahmood, and Asaad F. Albayati. "Reflections of the Anti-inflammatory Properties of Aspirin on Cardiovascular Disease and Diabetes Mellitus-related Pathological Markers." Systematic Reviews in Pharmacy 11.7 (2020), 393-395. Print. doi:10.31838/srp.2020.7.58 APA (American Psychological Association) Style Abdlwahid, H. M., Mahmood, . M. M. & Albayati, . A. F. (2020) Reflections of the Anti-inflammatory Properties of Aspirin on Cardiovascular Disease and Diabetes Mellitus-related Pathological Markers. Systematic Reviews in Pharmacy, 11 (7), 393-395. doi:10.31838/srp.2020.7.58 |
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