Abstract

Kartikey Kumar60073*, Shalu Verma60074 and Vikash Jakhmola60075

Nanovesicular carriers called ethosomes are used for dermal delivery. Nanovesicular drug deliveries provide thorough insights into the most up-to-date and complete discussion about the preparation of drugs. Sebaceous glands, hair follicles, and the pilosebaceous unit are all impacted by the chronic inflammatory disorder known as acne vulgaris. It is among the most prevalent dermatological problems in the globe. Water, ethanol in quite high concentrations (up to 50%), and phospholipids are the main components of ethosomes. Due to the presence of ethanol, ethosomes are referred to as “soft vesicles” with fluid bilayers. The vesicle form and content make them able to carry more molecules with a variety of physicochemical qualities to the skin’s deep layers. Ethosomal systems have been the subject of intensive study ever since they were initially proposed for a variety of purposes. In addition to the face, the back and chest can also be affected by acne, which can manifest as non-inflammatory lesions, combustible sores, or a mix of these two types. Ethosomes improve the drug’s penetration of the skin via transdermal and dermal distribution. A wide range of medications, including peptides and protein compounds, may be delivered via ethosomes. This review is about the ethosomes used for the treatment of acne vulgaris.