Role of Natural Polymers in the Development of Multiparticulate Systems for Colon Drug Targeting

Abstract

Das S, Deshmukh R, Jha AK

Colon-specific drug delivery has gained increased importance for the delivery of drugs for the treatment of local diseases associated with the colon. To deliver the compounds in a nondegraded form to the lower part of the gastrointestinal tract, they must first of all pass through the stomach, the upper part of the intestine and must use the characteristics of the colon to specifically release the drugs in this part of the digestive tract. The use of biodegradable polymers holds great promise to achieve targeted drug release to the colon. The family of natural polymers has great appeal to drug delivery as it comprises polymers with a large number of derivatizable groups, a wide range of molecular weights, varying chemical compositions, low toxicity, and biodegradability yet high stability. Polysaccharidases are bacterial enzymes that are available in sufficient quantity to degrade these natural polysaccharides. This article also discusses few delivery systems designed to target a drug to the colon.

How to Cite this Article
Pubmed Style

Das S, Deshmukh R, Jha AK. Role of Natural Polymers in the Development of Multiparticulate Systems for Colon Drug Targeting. SRP. 2010; 1(1): 79-85.
doi:10.4103/0975-8453.59516

Web Style

Das S, Deshmukh R, Jha AK. Role of Natural Polymers in the Development of Multiparticulate Systems for Colon Drug Targeting. http://www.sysrevpharm.org/?mno=302644634 [Access: March 28, 2021]. doi:10.4103/0975-8453.59516

AMA (American Medical Association) Style

Das S, Deshmukh R, Jha AK. Role of Natural Polymers in the Development of Multiparticulate Systems for Colon Drug Targeting. SRP. 2010; 1(1): 79-85. doi:10.4103/0975-8453.59516



Vancouver/ICMJE Style

Das S, Deshmukh R, Jha AK. Role of Natural Polymers in the Development of Multiparticulate Systems for Colon Drug Targeting. SRP. (2010), [cited March 28, 2021]; 1(1): 79-85. doi:10.4103/0975-8453.59516



Harvard Style

Das S, Deshmukh R, Jha AK (2010) Role of Natural Polymers in the Development of Multiparticulate Systems for Colon Drug Targeting. SRP, 1 (1), 79-85. doi:10.4103/0975-8453.59516



Turabian Style

Das S, Deshmukh R, Jha AK. 2010. Role of Natural Polymers in the Development of Multiparticulate Systems for Colon Drug Targeting. Systematic Reviews in Pharmacy, 1 (1), 79-85. doi:10.4103/0975-8453.59516



Chicago Style

Das S, Deshmukh R, Jha AK. "Role of Natural Polymers in the Development of Multiparticulate Systems for Colon Drug Targeting." Systematic Reviews in Pharmacy 1 (2010), 79-85. doi:10.4103/0975-8453.59516



MLA (The Modern Language Association) Style

Das S, Deshmukh R, Jha AK. "Role of Natural Polymers in the Development of Multiparticulate Systems for Colon Drug Targeting." Systematic Reviews in Pharmacy 1.1 (2010), 79-85. Print. doi:10.4103/0975-8453.59516



APA (American Psychological Association) Style

Das S, Deshmukh R, Jha AK (2010) Role of Natural Polymers in the Development of Multiparticulate Systems for Colon Drug Targeting. Systematic Reviews in Pharmacy, 1 (1), 79-85. doi:10.4103/0975-8453.59516

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