Spectrophotometric and Colorimetric Determination of Pharmaceutical by Oxidative Coupling Reaction: A Review
Aseel M. Aljeboree
The expansion of the pharmaceuticals imparted a revolt in health human.These pharmaceuticals would avail their sake only if they are liberated from pollution and used in amount suitable. Create pharmaceuticals avail their purpose several instrumental and chemical way were developed at uniform period which are include in the determination of pharmaceuticals. A simple, selective and sensitive spectrophotometric way has been advanced for the quantitative determination of several antibiotic drugs The way was based on the reaction of coupling oxidative drug organic with reagent in thefound of oxidizing agent to give colored product the absorbance of which is observed at wavelengths. The reactions of the Oxidative coupling recently utilized for determination spectrophotometric of different drugs such as thiamine hydrochloride (THC), salbutamol, phenylephrine, folic acid, catecholamine and amoxicillin drugs.