Spectrophotometric Determination of Mesalazine via Oxidative Coupling Reaction
Abstract
Ahlam Ahmed Shehab, Dawood Habboo Muhammed
A simple and sensitive spectrophotometric method for the determination of a mesalazine in the aqueous solution. The method is based on the oxidative coupling reaction between mesalazine and Phenothiazine in the presence of potassium dichromate as oxidizing agent to forming a green color water soluble dye showing maximum absorbance at 610nm. Beer’s law is obeyed in the concentration range of (0.1-11) µg/ml, with Correlation confection (R2 ) value more than 0.999.Molar absorptivity (2.055x10?) L.mole-1 .cm-1 and Sandall’s sensitivity (0.007451) µg/cm2 . This method has been successfully applied for the determination of mesalazine in various pharmaceutical preparations.
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| Pubmed Style Marwan Thaer Jalal. “Spectrophotometric Determination of Trifluoperazine Hydrochloride in Pharmaceutical Preparations by Oxidative Coupling Reaction”. SRP. 2020; 11(6): 58-68. doi:10.31838/srp.2020.6.12 Web Style Marwan Thaer Jalal. “Spectrophotometric Determination of Trifluoperazine Hydrochloride in Pharmaceutical Preparations by Oxidative Coupling Reaction”. http://www.sysrevpharm.org/?mno=112575 [Access: March 29, 2021]. doi:10.31838/srp.2020.6.12 AMA (American Medical Association) Style Marwan Thaer Jalal. “Spectrophotometric Determination of Trifluoperazine Hydrochloride in Pharmaceutical Preparations by Oxidative Coupling Reaction”. SRP. 2020; 11(6): 58-68. doi:10.31838/srp.2020.6.12 Vancouver/ICMJE Style Marwan Thaer Jalal. “Spectrophotometric Determination of Trifluoperazine Hydrochloride in Pharmaceutical Preparations by Oxidative Coupling Reaction”. SRP. (2020), [cited March 29, 2021]; 11(6): 58-68. doi:10.31838/srp.2020.6.12 Harvard Style Marwan Thaer Jalal (2020) “Spectrophotometric Determination of Trifluoperazine Hydrochloride in Pharmaceutical Preparations by Oxidative Coupling Reaction”. SRP, 11 (6), 58-68. doi:10.31838/srp.2020.6.12 Turabian Style Marwan Thaer Jalal. 2020. “Spectrophotometric Determination of Trifluoperazine Hydrochloride in Pharmaceutical Preparations by Oxidative Coupling Reaction”. Systematic Reviews in Pharmacy, 11 (6), 58-68. doi:10.31838/srp.2020.6.12 Chicago Style Marwan Thaer Jalal. "“Spectrophotometric Determination of Trifluoperazine Hydrochloride in Pharmaceutical Preparations by Oxidative Coupling Reaction”." Systematic Reviews in Pharmacy 11 (2020), 58-68. doi:10.31838/srp.2020.6.12 MLA (The Modern Language Association) Style Marwan Thaer Jalal. "“Spectrophotometric Determination of Trifluoperazine Hydrochloride in Pharmaceutical Preparations by Oxidative Coupling Reaction”." Systematic Reviews in Pharmacy 11.6 (2020), 58-68. Print. doi:10.31838/srp.2020.6.12 APA (American Psychological Association) Style Marwan Thaer Jalal (2020) “Spectrophotometric Determination of Trifluoperazine Hydrochloride in Pharmaceutical Preparations by Oxidative Coupling Reaction”. Systematic Reviews in Pharmacy, 11 (6), 58-68. doi:10.31838/srp.2020.6.12 |
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