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Study the Effect of Gabapentin on the Histology of Some Organs of Male rats

Abstract

Fakhir M. ALzubaidy, Aymen A Bash, Raad Jasim.

Background: Gabapentin is 1-(amino methyl) cyclohexane acetic acid with a molecular formula C9H17NO2. It used for the treatment of epilepsy, neuropathic pain, treatment of uremic pruritus, post-herptic neuralgia, and others.
Materials and methods: Eight adults white male rats were used, five of these animals were treated orally with Gabapentin 300 mg/ day, while three rats were used as a control and treated with DW.
Results and discussion: According to the histological sections, results showed no serious effects in the histology of liver, kidney, pancreas and spleen, and there is a few lymphocyte infiltrations have been observed in the liver tissue. These results were found to be compatible with previous studies, and this may reflect the safety of gabapentin regarding the histology of liver, kidney, pancreas and spleen.

 

How to Cite this Article
Pubmed Style

ALzubaidy FM, Bash AA, Jasim R. Study the Effect of Gabapentin on the Histology of Some Organs of Male rats. SRP. 2020; 11(9): 95-101. doi:10.31838/srp.2020.9.16

Web Style

ALzubaidy FM, Bash AA, Jasim R. Study the Effect of Gabapentin on the Histology of Some Organs of Male rats. http://www.sysrevpharm.org/?mno=138320 [Access: March 29, 2021]. doi:10.31838/srp.2020.9.16

AMA (American Medical Association) Style

ALzubaidy FM, Bash AA, Jasim R. Study the Effect of Gabapentin on the Histology of Some Organs of Male rats. SRP. 2020; 11(9): 95-101. doi:10.31838/srp.2020.9.16


Vancouver/ICMJE Style

ALzubaidy FM, Bash AA, Jasim R. Study the Effect of Gabapentin on the Histology of Some Organs of Male rats. SRP. (2020), [cited March 29, 2021]; 11(9): 95-101. doi:10.31838/srp.2020.9.16


Harvard Style

ALzubaidy, F. M., Bash, . A. A. & Jasim, . R. (2020) Study the Effect of Gabapentin on the Histology of Some Organs of Male rats. SRP, 11 (9), 95-101. doi:10.31838/srp.2020.9.16


Turabian Style

ALzubaidy, Fakhir M., Aymen A Bash, and Raad Jasim. 2020. Study the Effect of Gabapentin on the Histology of Some Organs of Male rats. Systematic Reviews in Pharmacy, 11 (9), 95-101. doi:10.31838/srp.2020.9.16


Chicago Style

ALzubaidy, Fakhir M., Aymen A Bash, and Raad Jasim. "Study the Effect of Gabapentin on the Histology of Some Organs of Male rats." Systematic Reviews in Pharmacy 11 (2020), 95-101. doi:10.31838/srp.2020.9.16


MLA (The Modern Language Association) Style

ALzubaidy, Fakhir M., Aymen A Bash, and Raad Jasim. "Study the Effect of Gabapentin on the Histology of Some Organs of Male rats." Systematic Reviews in Pharmacy 11.9 (2020), 95-101. Print. doi:10.31838/srp.2020.9.16


APA (American Psychological Association) Style

ALzubaidy, F. M., Bash, . A. A. & Jasim, . R. (2020) Study the Effect of Gabapentin on the Histology of Some Organs of Male rats. Systematic Reviews in Pharmacy, 11 (9), 95-101. doi:10.31838/srp.2020.9.16

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