Synthesis And Characterization Of New Schiff Bases And Their 1,3-Oxazepines Derived From Phthalic Anhydride
Abstract
Sahar F. Abbas, Jummbad H. Tomma, Emad T. Ali.
In this work one mole of 4-methyl aniline was allowed to react with one mole of phthalic anhydride to produce 2- [N- (4-methyl phenyl)] Phthalamic acid [I]. Which was submitted to esterification via the reaction with dimethylsulphat in anhydrous sodium carbonate in acetone as a solvent to synthesis new ester of 2-[N- (4-methyl phenyl ) ] Phthalamide acetate [II]. The condensation of ester [II] with hydrazine using ethanol as a solvent led to formation the acorresbonding 2-[N- (4-methyl phenyl ) ]- Phthalamic acid hydrazide [III] which reacted with aromatic aldehydes (anisaldehyde , N,N dimethyl benzaldehyde , 4-hydroxy benzaldehyde , 4-methyl benzaldehyde ) in some drops of glacial acetic acid and ethanol to yield new Schiff bases [IV]a-d . 1,3-oxazepine derivatives [V]a-d can be synthesized form reaction of Schiff bases [IV]a-d with phthalic anhydride in dry benzene to obtain new 1,3-oxazepines [V]a-d. All the synthesized compoundes were characterized by their FTIR and 1HNMR for (some of them).
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| Pubmed Style Sahar F. Abbas, Jummbad H. Tomma, Emad T. Ali. Synthesis And Characterization Of New Schiff Bases And Their 1,3-Oxazepines Derived From Phthalic Anhydride. SRP. 2021; 12(2): 260-265. doi:10.31838/srp.2021.2.33 Web Style Sahar F. Abbas, Jummbad H. Tomma, Emad T. Ali. Synthesis And Characterization Of New Schiff Bases And Their 1,3-Oxazepines Derived From Phthalic Anhydride. http://www.sysrevpharm.org/?mno=30951 [Access: March 29, 2021]. doi:10.31838/srp.2021.2.33 AMA (American Medical Association) Style Sahar F. Abbas, Jummbad H. Tomma, Emad T. Ali. Synthesis And Characterization Of New Schiff Bases And Their 1,3-Oxazepines Derived From Phthalic Anhydride. SRP. 2021; 12(2): 260-265. doi:10.31838/srp.2021.2.33 Vancouver/ICMJE Style Sahar F. Abbas, Jummbad H. Tomma, Emad T. Ali. Synthesis And Characterization Of New Schiff Bases And Their 1,3-Oxazepines Derived From Phthalic Anhydride. SRP. (2021), [cited March 29, 2021]; 12(2): 260-265. doi:10.31838/srp.2021.2.33 Harvard Style Sahar F. Abbas, Jummbad H. Tomma, Emad T. Ali (2021) Synthesis And Characterization Of New Schiff Bases And Their 1,3-Oxazepines Derived From Phthalic Anhydride. SRP, 12 (2), 260-265. doi:10.31838/srp.2021.2.33 Turabian Style Sahar F. Abbas, Jummbad H. Tomma, Emad T. Ali. 2021. Synthesis And Characterization Of New Schiff Bases And Their 1,3-Oxazepines Derived From Phthalic Anhydride. Systematic Reviews in Pharmacy, 12 (2), 260-265. doi:10.31838/srp.2021.2.33 Chicago Style Sahar F. Abbas, Jummbad H. Tomma, Emad T. Ali. "Synthesis And Characterization Of New Schiff Bases And Their 1,3-Oxazepines Derived From Phthalic Anhydride." Systematic Reviews in Pharmacy 12 (2021), 260-265. doi:10.31838/srp.2021.2.33 MLA (The Modern Language Association) Style Sahar F. Abbas, Jummbad H. Tomma, Emad T. Ali. "Synthesis And Characterization Of New Schiff Bases And Their 1,3-Oxazepines Derived From Phthalic Anhydride." Systematic Reviews in Pharmacy 12.2 (2021), 260-265. Print. doi:10.31838/srp.2021.2.33 APA (American Psychological Association) Style Sahar F. Abbas, Jummbad H. Tomma, Emad T. Ali (2021) Synthesis And Characterization Of New Schiff Bases And Their 1,3-Oxazepines Derived From Phthalic Anhydride. Systematic Reviews in Pharmacy, 12 (2), 260-265. doi:10.31838/srp.2021.2.33 |
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