The Antihyperglycemic Effect of N-butanol Leaves Extracts of Iraqi Fumaria parviflora on Alloxan-prompt Diabetic Rats

Abstract

Omar Hussein Ahmed, Enas Jawad Kadheem, Shathel Khalaf Noman.

Objective: This research examined Fumaria parviflora (f. parviflora) leaves and implied mechanisms with the use of in vivo hyperglycemia models.
Materials and Methods: The study included fifty Wistar rats from 180-220 g. Ethanolytic soxhlet extract of the F pads. Parviflora (EFP) was developed. Two weeks of oral remedy for the extract (500-100, or 200 mg / kg / day), metformin (200 mg / kg / day), diabetic rats. Other animals are only given extract, alloxan or vehicle control.
Results: Plant Extract Pretreatment Effect of diabetes rats The levels of blood glucose were lower (p < 0,05) relative to the amount of alloxane alone in rats treated for plant extraction, with normal levels of glucose at the begin of the experiment being between 73,00±1.5 and76,00±0,54 mg / dL. Blood glucose decreased during extraction in these animals, but values achieved were less important than the 14th day p < 0,05 control values.
Conclusion: F sheets in alloxane-induced rats the results of the study showed F. The effect of lowering blood glucose decreases. Parviflora has a significant effect on normal rat blood glycosis due to diabetes rats.