The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine

Abstract

Suwoyo, Lumastari Ajeng Wijayanti, Dwi Estuning Rahayu.

Measles is an infectious disease that attacks children. The incidence of measles in Indonesia is still quite high. The results of the immunization implementation report stated that the achievement of immunization targets for children under five reached more than 90%. However, not all children in Indonesia can enjoy the benefits of the immunization that has been given. Humans in their lives cannot avoid benzo [a] pyrene compounds, either directly or indirectly. The effect of benzo [a] pyrene on changes in immune cell profile in mice (Mus musculus L) was analyzed in vivo by giving intra-muscular injection of benzo [a] pyrene 20 mg / kg BW 2 times / week for 4 weeks. Immune cell profiles were analyzed using flowcytometry. The analysis was continued with statistical analysis using SPSS software using the one way ANOVA test with a significance level (p-value <0.05). The immune cell profile after week 4 in the group of mice that had received the vaccine and given exposure to benzo [a] pyrene was repression occurred in CD11b + IL1 +, CD11b + IL17 + activation occurred, while CD4 + CD25 + cell profiles experienced a downregulation reaction.

How to Cite this Article
Pubmed Style

, Wijayanti LA, Rahayu DE. The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine. SRP. 2020; 11(9): 926-930. 
doi:10.31838/srp.2020.9.135

Web Style

, Wijayanti LA, Rahayu DE. The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine. http://www.sysrevpharm.org/?mno=23317 [Access: March 30, 2021]. doi:10.31838/srp.2020.9.135

AMA (American Medical Association) Style

, Wijayanti LA, Rahayu DE. The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine. SRP. 2020; 11(9): 926-930. doi:10.31838/srp.2020.9.135



Vancouver/ICMJE Style

, Wijayanti LA, Rahayu DE. The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine. SRP. (2020), [cited March 30, 2021]; 11(9): 926-930. doi:10.31838/srp.2020.9.135



Harvard Style

, Wijayanti, . L. A. & Rahayu, . D. E. (2020) The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine. SRP, 11 (9), 926-930. doi:10.31838/srp.2020.9.135



Turabian Style

, Lumastari Ajeng Wijayanti, and Dwi Estuning Rahayu. 2020. The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine. Systematic Reviews in Pharmacy, 11 (9), 926-930. doi:10.31838/srp.2020.9.135



Chicago Style

, Lumastari Ajeng Wijayanti, and Dwi Estuning Rahayu. "The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine." Systematic Reviews in Pharmacy 11 (2020), 926-930. doi:10.31838/srp.2020.9.135



MLA (The Modern Language Association) Style

, Lumastari Ajeng Wijayanti, and Dwi Estuning Rahayu. "The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine." Systematic Reviews in Pharmacy 11.9 (2020), 926-930. Print. doi:10.31838/srp.2020.9.135



APA (American Psychological Association) Style

, Wijayanti, . L. A. & Rahayu, . D. E. (2020) The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine. Systematic Reviews in Pharmacy, 11 (9), 926-930. doi:10.31838/srp.2020.9.135

Most Viewed Articles
  • Dental Development between Assisted Reproductive Therapy (Art) and Natural Conceived Children: A Comparative Pilot Study Norzaiti Mohd Kenali, Naimah Hasanah Mohd Fathil, Norbasyirah Bohari, Ahmad Faisal Ismail, Roszaman Ramli SRP. 2020; 11(1): 01-06 » doi: 10.5530/srp.2020.1.01
  • Psychometric properties of the World Health Organization Quality of life instrument, short form: Validity in the Vietnamese healthcare context Trung Quang Vo*, Bao Tran Thuy Tran, Ngan Thuy Nguyen, Tram ThiHuyen Nguyen, Thuy Phan Chung Tran SRP. 2020; 11(1): 14-22 » doi: 10.5530/srp.2019.1.3
  • A Review of Pharmacoeconomics: the key to “Healthcare for All” Hasamnis AA, Patil SS, Shaik Imam, Narendiran K SRP. 2019; 10(1): s40-s42 » doi: 10.5530/srp.2019.1s.21
  • Deuterium Depleted Water as an Adjuvant in Treatment of Cancer Anton Syroeshkin, Olga Levitskaya, Elena Uspenskaya, Tatiana Pleteneva, Daria Romaykina, Daria Ermakova SRP. 2019; 10(1): 112-117 » doi: 10.5530/srp.2019.1.19
Most Downloaded
  • Dental Development between Assisted Reproductive Therapy (Art) and Natural Conceived Children: A Comparative Pilot Study Norzaiti Mohd Kenali, Naimah Hasanah Mohd Fathil, Norbasyirah Bohari, Ahmad Faisal Ismail, Roszaman Ramli SRP. 2020; 11(1): 01-06 » doi: 10.5530/srp.2020.1.01
  • Manilkara zapota (L.) Royen Fruit Peel: A Phytochemical and Pharmacological Review Karle Pravin P, Dhawale Shashikant C SRP. 2019; 10(1): 11-14 » doi: 0.5530/srp.2019.1.2
  • Pharmacognostic and Phytopharmacological Overview on Bombax ceiba Pankaj Haribhau Chaudhary, Mukund Ganeshrao Tawar SRP. 2019; 10(1): 20-25 » doi: 10.5530/srp.2019.1.4
  • A Review of Pharmacoeconomics: the key to “Healthcare for All” Hasamnis AA, Patil SS, Shaik Imam, Narendiran K SRP. 2019; 10(1): s40-s42 » doi: 10.5530/srp.2019.1s.21
  • A Prospective Review on Phyto-Pharmacological Aspects of Andrographis paniculata Govindraj Akilandeswari, Arumugam Vijaya Anand, Palanisamy Sampathkumar, Puthamohan Vinayaga Moorthi, Basavaraju Preethi SRP. 2019; 10(1): 15-19 » doi: 10.5530/srp.2019.1.3