The Effect of Il-6 Enhancement Due to Oral Cavity Infection on Skeletal Muscle
Abstract
Risma Aprianda Kristanti, Aulia Ramadhani, R Darmawan Setijanto
One of the cytokines that often play a role in the body's response mechanism to infections, inflammation, and various other diseases is Interleukin-6 (IL-6). The role of IL-6 is determined by the signaling mechanism involving various intracellular molecules. Oral infection that can cause an increase in IL-6 level mainly is periodontitis. In periodontitis, the increased level of IL-6 do not only occur locally, but also systemically, in which it affects several tissues, one of which is skeletal muscle. Several studies have proven that the enhancement of IL-6 levels which are caused by oral cavity infections influences the skeletal muscle tissue in both humans and experimental animals. The results of the IL-6 signaling can result in the reduction of muscle mass. The mechanism of IL-6 level enhancement, which results from the host response to oral cavity infections affecting skeletal muscle, is still being discussed and investigated further.
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| Pubmed Style Risma Aprianda Kristanti, Aulia Ramadhani, R Darmawan Setijanto. The Effect of Il-6 Enhancement Due to Oral Cavity Infection on Skeletal Muscle. SRP. 2020; 11(5): 597-602. doi:10.31838/srp.2020.5.81 Web Style Risma Aprianda Kristanti, Aulia Ramadhani, R Darmawan Setijanto. The Effect of Il-6 Enhancement Due to Oral Cavity Infection on Skeletal Muscle. http://www.sysrevpharm.org/?mno=112504 [Access: March 29, 2021]. doi:10.31838/srp.2020.5.81 AMA (American Medical Association) Style Risma Aprianda Kristanti, Aulia Ramadhani, R Darmawan Setijanto. The Effect of Il-6 Enhancement Due to Oral Cavity Infection on Skeletal Muscle. SRP. 2020; 11(5): 597-602. doi:10.31838/srp.2020.5.81 Vancouver/ICMJE Style Risma Aprianda Kristanti, Aulia Ramadhani, R Darmawan Setijanto. The Effect of Il-6 Enhancement Due to Oral Cavity Infection on Skeletal Muscle. SRP. (2020), [cited March 29, 2021]; 11(5): 597-602. doi:10.31838/srp.2020.5.81 Harvard Style Risma Aprianda Kristanti, Aulia Ramadhani, R Darmawan Setijanto (2020) The Effect of Il-6 Enhancement Due to Oral Cavity Infection on Skeletal Muscle. SRP, 11 (5), 597-602. doi:10.31838/srp.2020.5.81 Turabian Style Risma Aprianda Kristanti, Aulia Ramadhani, R Darmawan Setijanto. 2020. The Effect of Il-6 Enhancement Due to Oral Cavity Infection on Skeletal Muscle. Systematic Reviews in Pharmacy, 11 (5), 597-602. doi:10.31838/srp.2020.5.81 Chicago Style Risma Aprianda Kristanti, Aulia Ramadhani, R Darmawan Setijanto. "The Effect of Il-6 Enhancement Due to Oral Cavity Infection on Skeletal Muscle." Systematic Reviews in Pharmacy 11 (2020), 597-602. doi:10.31838/srp.2020.5.81 MLA (The Modern Language Association) Style Risma Aprianda Kristanti, Aulia Ramadhani, R Darmawan Setijanto. "The Effect of Il-6 Enhancement Due to Oral Cavity Infection on Skeletal Muscle." Systematic Reviews in Pharmacy 11.5 (2020), 597-602. Print. doi:10.31838/srp.2020.5.81 APA (American Psychological Association) Style Risma Aprianda Kristanti, Aulia Ramadhani, R Darmawan Setijanto (2020) The Effect of Il-6 Enhancement Due to Oral Cavity Infection on Skeletal Muscle. Systematic Reviews in Pharmacy, 11 (5), 597-602. doi:10.31838/srp.2020.5.81 |
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