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The Therapeutic Effect Of Eucalyptus Microtheca Against The Giardiasis Induced Renal Damage In Male Rats

Abstract

Abdulrazzaq Mohammed Hammood, Muhannad Shweash, and Hazim Ghazzay

The current study was designed to show the role of aqueous crude extracts against the Giardia lamblia. The study used 20 rats (Adult male) that distributed into four groups; the control group. Second group rat infected with (1X103 cell/ ml) G. lamblia. The third group infected rat was treated with (100mg/ml) aqueous extract for four weeks. The fourth group infected rat was treated with (250mg/ml) aqueous extract for four weeks. The results show a highly significant elevate (P < 0.05) in levels of MDA with a significant (P < 0.05) reduction in levels of catalase in infected rats compared with the control group. The results of treated rats show non-significant (P < 0.05) changes in all parameters compare with the control group when using aqueous crude extracts. About the histological changes, in the second group, kidney sections show damage glomerulus, slough endothelial of tubules, lymphocytes infiltration, thickening wall of blood vessels, and fibroblast. In treated groups (100mg & 250mg), show semi-normal glomerulus and urinary tubules. So, an aqueous extract of E. microtheca show a high efficacy role against G. lamblia.

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