Topical Minoxidil Alone and with Topical Lanoprost in Localized Alopecia Areata Treatment: Comparative Study (2019-2020)

Abstract

Ahmed Abdulhussein Kawen.

Rationale: Therapeutic choicement for patients with alopacia was of limited success, no hundred percent cure rate, and no choice for absolute remission without recrudescence.
Aim: Comparison of topical Lanoprost & Minoxidil versus topical Minoxidil only in treatment of localized alopecia areata.
Methodology: Interventional-controlled single blinded study that was involving (95) alopecia areata patients. That extended from1st day of February 2019 to last week January 2020 In Al-Hussain teaching hospitals in Thi-Qar and Al-Muthana governorates., the patients crossly matched well and divided according to lines of treatment into two groups. ethical consent had been taken after full details explanation of research items and purpose.
Results: Post interventional assessment of the response difference in terms significant statistical differences (p value=0.002, 0.0001) between the two groups. The SALT II when compared before and after treatment was decreasing in both groups but to a significantly better extent in group II
Conclusions: The treatments with 5% minoxidil in a combination with 0.005% latanoprost or 5% minoxidil alone were found to be effective and a better result with minoxidil only. implemented combination in the managements of alopecia areata is of great benefit in reduction of size and duration of treatment.