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Traditional and Novel Methods for Cocrystal Formation: A Mini Review

Abstract

Kuni Zu’aimah Barikah*

Pharmaceutical cocrystal is one of solid-state modification for drug sub-stance, mainly for solubility improvement. Traditionally, cocrystal can be prepared by solvent evaporation method, grinding, and slurry method, but, every method has limitation for certain condition. The current trend for cocrystal formation uses the sophisticated method such as hot-melt extru-sion method, spray drying method, supercritical fluid technology and the newest, and laser irradiation method. Development of new method is not only to overcome the limitation of traditional cocrystallization methods but also to generate a simpler step and continuous process for the production of cocrystal product. This article gives a brief explanation of each method that can be used to generate pharmaceutical cocrystals.

 

How to Cite this Article
Pubmed Style

Kuni Zu'aimah Barikah. Traditional and Novel Methods for Cocrystal Formation: A Mini Review. SRP. 2018; 9(1): 79-82. doi:10.5530/srp.2018.1.15

Web Style

Kuni Zu'aimah Barikah. Traditional and Novel Methods for Cocrystal Formation: A Mini Review. http://www.sysrevpharm.org/?mno=302644553 [Access: March 28, 2021]. doi:10.5530/srp.2018.1.15

AMA (American Medical Association) Style

Kuni Zu'aimah Barikah. Traditional and Novel Methods for Cocrystal Formation: A Mini Review. SRP. 2018; 9(1): 79-82. doi:10.5530/srp.2018.1.15


Vancouver/ICMJE Style

Kuni Zu'aimah Barikah. Traditional and Novel Methods for Cocrystal Formation: A Mini Review. SRP. (2018), [cited March 28, 2021]; 9(1): 79-82. doi:10.5530/srp.2018.1.15


Harvard Style

Kuni Zu'aimah Barikah (2018) Traditional and Novel Methods for Cocrystal Formation: A Mini Review. SRP, 9 (1), 79-82. doi:10.5530/srp.2018.1.15


Turabian Style

Kuni Zu'aimah Barikah. 2018. Traditional and Novel Methods for Cocrystal Formation: A Mini Review. Systematic Reviews in Pharmacy, 9 (1), 79-82. doi:10.5530/srp.2018.1.15


Chicago Style

Kuni Zu'aimah Barikah. "Traditional and Novel Methods for Cocrystal Formation: A Mini Review." Systematic Reviews in Pharmacy 9 (2018), 79-82. doi:10.5530/srp.2018.1.15


MLA (The Modern Language Association) Style

Kuni Zu'aimah Barikah. "Traditional and Novel Methods for Cocrystal Formation: A Mini Review." Systematic Reviews in Pharmacy 9.1 (2018), 79-82. Print. doi:10.5530/srp.2018.1.15


APA (American Psychological Association) Style

Kuni Zu'aimah Barikah (2018) Traditional and Novel Methods for Cocrystal Formation: A Mini Review. Systematic Reviews in Pharmacy, 9 (1), 79-82. doi:10.5530/srp.2018.1.15

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