Aike Shi

Department of Neurology, Sun-Yet-Sen University, Guang Dong, China


  • Review Article   
    Effects of Brain-Derived Neurotrophic Factor (BDNF) and Ankyrin 3 (ANK3) in Bipolar Disorder
    Author(s): Aike Shi50700*

    Bipolar Disorder (BD) is a mental disorder with emotional highs (euphoria) and lows, diagnosed especially in teenage years and early adulthood, which can cause cyclings containing manic (hypomanic) episodes and major depressive episodes. Nowadays, the suicide death rate of BD increases dramatically, thus BD has attracted more attention of society. So far, numerous studies have argued that it is heavily influenced by genetics, and BDNF (Brain-Derived Neurotrophic Factor) and ANK3 (Ankyrin 3) are regarded as the most important risk factors to BD susceptibility. Furthermore, BDNF and ANK3 both play a key role in central nervous system, which means a small mutation or change of them will induce some significant consequences. This article summarizes some researches about the association between BDNF and BD and its typical rapid cycling, as well as the potential effects .. Read More»
    DOI: 10.31858/0975-8453.14.1.19-22

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