Angela Montone

Department of Public Health, University of Naples Federico II, Naples, Italy

Publications

  • Case Report   

    Author(s): Brogna Marianna60593*, Francesca Collina60596, Simona Losito60597, Eduardo Clery60598, Angela Montone60599, Michele Del Sesto60600 and Gerardo Ferrara60601

    Background: Papillary Thyroid Cancer (PTC) is the most common type of well differentiated endocrine malignancy. Generally thyroid nodules with multiple oncogenic mutations are uncommon with an occurrence which may be related to more aggressive biological behavior of tumors. Rearranged in Transformation/ Papillary Thyroid Carcinomas (RET/PTC) rearrangement, RAS and BRAF mutations are considered to be mutually exclusive in PTC. Concomitant RET/PTC, RAS, or BRAF mutations have been documented, although the impact of these mutations for tumor growth and survival is debated. Case presentation: Here, we present a rare case of woman 46 years old with a neck mass and thyroid nodule classified as Toll-Like Receptor 5 (TIR5) on cytological examination. We found contemporary BRAF p.(Val600Glu) (p. (V600E); c.. Read More»
    DOI: 10.31858/0975-8453.14.7.447-451

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