Karin Schulze-Bosse

Department of Virology, University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf, Germany


  • Review Article   
    SARS-CoV-2 Vaccination Companion Diagnostics: A Novel Perspective in Optimizing COVID-19 (Re-) Immunization
    Author(s): Anna Sabrina Kuechler41819*, Karin Schulze-Bosse41820 and Lisa Mller41821

    Until today, vaccination against COVID-19 is handled by fixed and blind immunization-schedules. This work overviews and discusses the opportunities and limitations of different Severe Acute Respiratory Syndrome Corona Virus type 2 (SARS-CoV-2) antibody tests and their suitability as SARS-CoV-2 vaccination companion diagnostics. These tests are not officially recommended for evaluating the necessity of (re-) immunization yet, but novel studies contribute to understanding their informative value, their complementary relationships and thus their potential for using them as a predictor for immune-protection against COVID-19. We found that serological assays detecting antibodies against SARS-CoV-2 and their neutralizing capacity can form a diagnostic strategy for individualized vaccination schedules due to their specific informative values.. Read More»
    DOI: 10.31858/0975-8453.13.6.699-704

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