Kübra Kelleci

Department of Medical Services and Techniques, Beykoz University, Istanbul, Turkey

Publications

  • Research Article   
    Determination of Immunostimulatory Efficacy of Benzimidazole Derivatives Against Leishmania infantum
    Author(s): Kübra Kelleci47809*

    Leishmaniasis is a parasitic disease affecting more than 12 million people worldwide. Although the use of chemotherapeutic drugs is among the current treatment methods, it is emphasized that the limitations of the drugs, their disadvantages such as insufficient safety and efficacy, the disease being endemic, and the need to develop drugs for this disease. In this study, in vitro anti-leishmanial activities of two benzimidazole derivatives (B1 and B2) were tested against L. infantum promastigote and amastigote for the first time. In our study, the anti-leishmanial effects of B1 and B2 on both amastigote and promastigote forms of Leishmania infantum were investigated using J774 macrophage cells. It was found that the tested compounds were not toxic to the host cell. In addition, when compared to the drug miltefosine, which is used worldwide in the treatment of.. Read More»
    DOI: 10.31858/0975-8453.13.12.826-830

    Abstract HTML PDF