Shwetha TL

Department of Pharmacy, East Point College of Pharmacy, Karnataka, India


  • Research Article   
    Formulation and Evaluation of Micro Sponges Loaded with Acyclovir Using an Antiviral Drug
    Author(s): Shwetha TL39989*, Srinivasan S39990 and Chandrakala V39991

    The main objective of the present research work was to develop and evaluate the anti-viral drug (Acyclovir) loaded micro sponges using polymers. Micro sponges of acyclovir were prepared by quassi-emulsion solvent diffusion method by using EC and HPMC as polymers. The prepared acyclovir micro sponges were subjected to IR, SEM, Particle size and Size distribution, Entrapment efficiency, in vitro dissolution studies and release kinetics. The IR Spectras revealed that, there was no interaction between the polymer and acyclovir. Acyclovir micro sponges was spherical in nature, which was confirmed by SEM. Acyclovir micro sponges with normal frequency distribution were obtained. A maximum of 95.67% drug entrapment efficiency was obtained in the acyclovir micro sponges. F5 formulations ACV micro sponges show the maximum drug release. The coefficient of determination indicated that th.. Read More»
    DOI: 10.31858/0975-8453.13.4.225-228

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