Vyshnavi C

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research, Andhra Pradesh, India


  • Research Article   

    Author(s): Gayathri S49085*, Jayanth Reddy K49086, Samuel Y49099, Vyshnavi C49100, Savithri D49101, Pavithra H49102, Nikhitha K49103 and Soma Sekhar Reddy K49104

    Stylosanthes fruticos, a perennial plant has been revered in ayurveda medicine for generations. The aim of the present study was to determine the antidiarrheal activity of ethanolic extract of S. fruticos (EESF), utilizing castor oil-induced, magnesium sulphate induced diarrhoea and castor oil-induced enteropooling in mice. The presence of alkaloids, carbohydrates, flavonoids,  steroids,  and  phenols  was  discovered by phytochemical screening of EESF. At 25 mg/kg of dosage, the EESF provided considerable significant (p<0.05) inhibition on castor oil-induced diarrhea, magnesium sulphate  induced  diarrhea  and  castor oil induced enteropooling. From the findings, it was evident that EESF had dose-dependent antidiarrheal effects in all treatment groups, and the results were also well comparable with loperamide (3 mg/kg).. Read More»
    DOI: 10.31858/0975-8453.14.1.6-10

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