Cerebral Venous Sinus Thrombosis (CVST): An Emerging Complication of SARS CoV-2 Infection

Abstract

Nicola Maggialetti22642, Alessandra Gualano22643*, Roberto Russo22644, Rocco Umberto Accogli22645 and Amato Antonio Stabile Ianora22646

Background: During Coronavirus (COVID-19) pandemic, SARS CoV-2 infection has been documented to be associated with thrombotic complications, especially pulmonary embolism, which are triggered by virus binding to ACE-2 receptors and consequent activation of a cascade leading to a hypercoagulable pathway, however Cerebral Venous Sinus Thrombosis (CVST) is emerging as a further thrombotic complication of COVID-19.

Case presentation: We report our experience of a patient affected by SARS CoV-2 infection, who presented to our emergency department with neurological symptoms such as confusion and headache and was diagnosed with CVST at imaging exams.

Conclusion: As neurological symptoms such as confusion and headache are aspecific and shared with patients affected by SARS CoV-2 infection in absence of CVST, clinicians should be aware of this emerging hematologic complication in order to recognize it as soon as possible and provide the best patient care.

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