Abhijit De

Department of Pharmaceutical Technology, Maulana Abul Kalam Azad University of Technology, West Bengal, India


  • Research Article   
    Effect of Vitamin U on High Fat Diet and Nicotine Induced Non-Alcoholic Fatty Liver Disease in Wistar Albino Rats
    Author(s): Indrajit Bhattacharya41825*, CM Hossain41826 and Abhijit De41827

    The liver plays an important function in the metabolism of carbohydrate-protein and fats. Now a day’s obesity and high fatty diet cigarettes increased Oxidative stress which leads to the chance of Non-Alcoholic Fatty Liver Disease (NAFLD). The main objective of this study was to evaluate the effect of Vitamin-U on a High-Fat Diet (HFD) and nicotine-induced NAFLD in rats. Female Wistar rats (n=6) that weighed 200-250 g were randomly segregated into six groups of nine animals in each group. The Group-I animals received a normal diet and the rest of the groups received HFD and nicotine (1.5 mg/kg, b.wt (body weight), I.P (Intraperitoneal)) (NAFLD control) and water ad libitum. After 28th days, blood was collected from the retro-orbital plexus under mild chloroform to ensure that all animals which received HFD and nicotine were hyperlipidemia or not. After conformation an.. Read More»
    DOI: 10.31858/0975-8453.13.9.610-617

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