Anshuman Trigunayat
Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi, IndiaPublications
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Research Article
Assessment of Pain-Ameliorative Potential of Ethanolic Extract of Calotropis procera and its Active Components characterization by HPTLC and GC-MS Analysis
Author(s): Ashutosh Kumar41172, Brijesh Kumar41173*, Rajesh Kumar41174, Ajay Kumar41175, Manish Singh41176, Pratistha Singh41177, Vinod Tiwari41178 and Anshuman Trigunayat41179
Introduction: Calotropis procera is a shrub had been used traditionally for the treatment of many diseases including analgesic, anti-inflammatory, hepatic and other diseases. The flower of the plant has not been investigated for its analgesic activity. The present study aims High Pressure Thin Layer Chromatography (HPTLC) and Gas Chromatography-Mass Spectrometry (GC-MS) analysis of Ethanolic Extract of Calotropis procera to evaluate the analgesic effects of Calotropis procera as well as assessment of analgesic activity in animal models. Methods: The ethanolic extracts were prepared using a rotary evaporator and the maceration procedure. The phytocompounds characterization was done by GC-MS and HPTLC. The hot plate method, acetic acid- induced writhing test, and tail-flick test were used to determine the analgesic .. Read More»
DOI: 10.31858/0975-8453.13.9.581-586