Indra Sen Singh

Department of Chemistry, School of Mathematics and Natural Sciences, The Copperbelt University, Kitwe, Zimbabwe


  • Research Article   
    GC-MS, GNPS and METLIN Assisted Phytochemical Profiling, Bioactivity Study and Molecular Docking Analysis of Paropsia brazzeana Root Bark, a Medicinal Plant in Zambia
    Author(s): Indra Sen Singh66230* and Sidney Muzyamba66232

    Medicinal plants have been used in Zambia as folk medicine from time immemorial. Ethnopharmacological studies have indicated that various parts of Paropsia brazzeana have been used to treat various ailments such as Venereal Diseases (VD), gastrointestinal complications, malaria, hernia, and toothaches while also possessing antibacterial, antispasmodic, antiamoebic activity and aphrodisiac potential. In the present study, we report the qualitative phytochemical screening, Gas Chromatography Mass Spectrometry (GC-MS) phytochemical profiling, Global Natural Product Social (GNPS) and (METLIN) Gen 2 Database assisted molecular mining, total phenolic content, total flavonoid content, in vitro antioxidant activity of crude root bark extract, and molecular docking analysis of selected phytochemicals of Paropsia brazzeana. Qualitative phytochemical screening revealed.. Read More»
    DOI: 10.31858/0975-8453.15.1.1-14

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